Posilozin 10 mg (Dapagliflozin Monohydrate Mixture)

Adult dose

The recommended dose for this drug is 10 mg once daily for monotherapy and additional combination therapy with insulin or other blood glucose-lowering agents. When used in combination with insulin or insulin secretagogues such as sulfonylureas, lower doses of insulin or insulin secretagogues may be considered to reduce the risk of hypoglycemia. This drug can be taken once daily at any time of day, regardless of food intake.

Child dose

The efficacy and safety of dapagliflozin in pediatric patients under 18 years of age have not been established. No relevant data available.

This drug should not be administered to certain patients. For example, patients allergic to this drug's ingredients or additives, patients with type 1 diabetes, diabetic ketoacidosis patients, patients with genetic issues such as lactose intolerance, and patients undergoing dialysis should not use this drug. Caution should be exercised when administering this drug to patients with volume depletion or impaired kidney function. This drug may lower blood pressure or affect kidney function, thus patients with impaired kidney function, the elderly, and those taking diuretics should be carefully monitored regarding their fluid status and kidney function. This drug contains yellow pigments (Yellow No. 4, Yellow No. 5), so patients with allergic reactions to these ingredients should be cautious. Common side effects while taking this drug can include genital infections, urinary tract infections, hypoglycemia, volume depletion, dizziness, and dry mouth. In particular, genital infections may occur more frequently in women, so appropriate treatment is necessary if symptoms appear. Due to the risk of diabetic ketoacidosis, symptoms such as nausea, vomiting, abdominal pain, and shortness of breath should prompt an immediate visit to a hospital. Additionally, this drug may affect kidney function, so it is important for patients with impaired kidney function to regularly check their creatinine levels. While this drug helps control blood sugar, the risk of hypoglycemia may increase when used in combination with insulin or sulfonylureas, so dose adjustments for these medications may be necessary. It is safer for pregnant or breastfeeding women not to use this drug. In cases of overdose, since there is no specific antidote, it is important to receive appropriate treatment based on symptoms. Finally, this drug does not significantly affect driving or operating machinery, but caution is needed due to the risk of hypoglycemia. It is important to follow the doctor's advice for regular testing while taking this drug and to consult immediately if abnormal symptoms occur.

Serious side effects

Hives, severe swelling, chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, oral/ocular mucosal pain, shortness of breath or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, yellowing of the skin or eyes, extreme lethargy, sudden and very severe headache, thunderclap headache, seizures, confusion, vision abnormalities, paralysis, significant decrease in urine output

Mild side effects

• Vulvitis
• balanitis
• urinary tract infection
• fungal infection
• hypoglycemia
• volume depletion
• dizziness
• constipation
• dry mouth
• back pain

This drug should be stored in a tightly closed container to protect it from air and moisture. Additionally, it is advisable to store the drug at room temperature between 1 degree and 30 degrees Celsius, rather than in very hot or very cold places. Proper storage can help maintain the drug's effectiveness for a longer time.

Appearance

Yellow, double-convex rhombus-shaped film-coated tablets

Package unit

28 tablets/box [14 tablets/PTP x 2]