Youngil Sitagliptin Tablet 50 Milligrams (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dose of 100 mg, with a maximum daily dosage of 100 mg. For patients with renal impairment, mild to moderate renal impairment (glomerular filtration rate [eGFR] ≥ 45 mL/min/1.73 m2 or higher) do not require dosage adjustments, for moderate renal impairment (glomerular filtration rate [eGFR] between 30 and 45 mL/min/1.73 m2) a dose of 50 mg is administered once daily. In cases of severe renal impairment, dosage adjustment is necessary.

This medication may cause allergic reactions; if symptoms such as skin rash, difficulty breathing, swelling of the face or neck occur, discontinue use immediately and consult a doctor. This medication may cause serious inflammation of the pancreas called pancreatitis; if symptoms such as abdominal pain, nausea, vomiting, or fever occur while taking this medication, visit a hospital immediately. Do not use this medication in patients with type 1 diabetes or diabetic ketoacidosis, and do not administer it to individuals with a known allergy to this medication or its components. Patients with impaired kidney function should have their dosage adjusted and undergo periodic kidney function tests before and during therapy. Hypoglycemic symptoms may occur while taking this medication, so blood glucose levels should be checked frequently, and caution is needed if taken together with other hypoglycemic agents such as insulin or sulfonylureas, as this may increase the risk of hypoglycemia. This medication may cause side effects such as upper respiratory infection, nasopharyngitis, headache, indigestion, diarrhea, and dizziness. Symptoms that are severe or persistent should be discussed with a doctor. It is advisable for pregnant or breastfeeding women not to take this medication, and safety and efficacy have not been established in children or adolescents under 18 years of age. Elderly patients may have a risk of reduced kidney function, so dosage adjustment and kidney function tests are needed. In cases of overdose, measures to remove the drug from the gastrointestinal tract should be taken, and the condition should be monitored through tests such as an electrocardiogram; hemodialysis may be performed if necessary. This medication generally has low interaction with other drugs; however, it is advisable to consult with a doctor or pharmacist when taken with specific medications. If unusual symptoms such as severe joint pain or blistering of the skin occur during treatment, inform a physician immediately, and discontinue use if necessary.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, severe rash, skin peeling, mucosal pain in mouth/eyes (Stevens-Johnson syndrome), acute pancreatitis, difficulty breathing, severe allergic reactions, skin reactions, severe and disabling joint pain, blistering dermatitis similar to pemphigus, thrombocytopenia, acute renal failure, liver abnormalities (including elevated liver enzyme levels), hypoglycemia (including severe hypoglycemia), pneumonia, diabetes complications, metabolic acidosis

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• nausea
• indigestion
• dizziness
• increased blood triglycerides
• increased low-density lipoprotein
• hyperglycemia

This medication should be stored in a sealed container to prevent air exposure, at a temperature between 1 degrees to 30 degrees Celsius for optimal effect. This helps maintain the efficacy of the medication.

Appearance

Pale yellowish-pink round film-coated tablet with both sides convex

Package unit

30 tablets/box [10 tablets/PTP x 3]