Youngil Sitagliptin Tablets 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

The recommended dosage for this medication is 100 mg once daily as monotherapy or in combination therapy, with a maximum daily dosage of 100 mg. This medication can be taken regardless of meals. In patients with renal impairment, dosage adjustments are necessary based on kidney function. Mildly impaired renal function patients (eGFR 60-90 mL/min/1.73 m2) and moderately impaired renal function patients (eGFR 45-60 mL/min/1.73 m2) require dosage adjustments.

This medication may cause rare but severe allergic reactions, and if symptoms such as rash, difficulty breathing, or swelling of the face or neck occur after taking the medication, it should be discontinued immediately and a doctor consulted. During the use of this medication, acute pancreatitis may develop, so if severe abdominal pain or vomiting occurs, immediate medical attention is required. This medication should not be used by patients with type 1 diabetes or diabetic ketoacidosis, nor should it be administered to those with known allergies to this medication or its components. Patients with impaired kidney function should have their dosage adjusted, and regular kidney function tests are necessary before and during treatment. Since there is a risk of hypoglycemia, caution should be exercised for signs of low blood sugar while using this medication in conjunction with insulin or sulfonylureas, and dosage adjustments for those medications may be necessary. If severe joint pain occurs during the use of this medication, a doctor should be informed, and immediate medical attention is required for blisters or skin lesions. Pregnant or nursing women should not use this medication, and its safety and efficacy have not been established for children or adolescents under 18 years of age. Elderly patients may be at risk for diminished kidney function, so dosage adjustments and regular kidney function checks are necessary. In case of overdose, measures should be taken to remove the drug from the gastrointestinal tract, monitor the condition through ECG, and if necessary, some drug removal may be achieved through hemodialysis. Interactions with other medications taken concurrently with this medication are generally minimal, but if taking digoxin or cyclosporine, healthcare professionals should be informed for appropriate management. While using this medication, side effects such as infections, headaches, indigestion, and diarrhea may occur; if symptoms are severe or prolonged, consultation with a doctor is recommended.

Serious side effects

Urticaria, severe swelling (edema), anaphylaxis, angioedema, rash, exfoliative skin disease, Stevens-Johnson syndrome, acute pancreatitis (fatal/non-fatal hemorrhagic or necrotizing pancreatitis), acute renal failure, bullous pemphigoid, severe and disabling arthralgia, cardiac arrest, elevated liver enzymes, liver abnormalities (jaundice), pneumonia, diabetes complications, metabolic acidosis, severe hypoglycemia, rhabdomyolysis

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• vomiting
• muscle pain
• limb pain

This medication should be stored in a tightly sealed container to prevent exposure to air and moisture, and it is recommended to keep it at room temperature between 1 and 30 degrees Celsius. Proper storage will ensure the medication's efficacy is maintained safely.

Appearance

Light orange, round, double convex, film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP x 3]