Bielpezil Tablets 5 mg (Donepezil Hydrochloride Monohydrate)

Adult dose

As donepezil hydrochloride, the recommended dosage is 5 mg once daily before bedtime. If unusual dreams, nightmares, or sleep disturbances occur, consider morning dosing. Administer 5 mg for 4-6 weeks, and thereafter evaluate clinical response to increase to 10 mg if necessary. When increasing to 10 mg daily, exercise caution regarding gastrointestinal adverse reactions. Underweight female patients over 85 years should receive only 5 mg daily.

This medication should not be used by patients with allergies to specific ingredients, or by pregnant or breastfeeding women. Additionally, patients with lactose intolerance or certain genetic issues should avoid taking this medication. Patients with heart disease or problems with heart rhythm should be cautious as this medication may cause bradycardia or arrhythmias. Those taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should be careful of gastrointestinal bleeding or worsening of ulcers. Patients with asthma or obstructive pulmonary disease should also be cautious as symptoms may worsen due to bronchoconstriction and increased mucus production. Patients with extrapyramidal disorders like Parkinson's disease need to be cautious as their symptoms may worsen. While taking this medication, serious side effects such as slowed heart rate, fainting, heart attack, gastrointestinal bleeding, liver dysfunction, seizures, and muscle disorders may occur; if symptoms arise, consult a healthcare professional immediately. Furthermore, various side effects like nausea, vomiting, diarrhea, dizziness, insomnia, hallucinations, depression, and muscle pain may occur, so it's important to carefully monitor for unusual symptoms. This medication is used solely for the treatment of dementia and is not approved for other forms of cognitive impairment. Periodic evaluation of treatment effectiveness should be conducted and discontinuation considered if necessary. This medication can affect heart rhythm, so it should be used cautiously in patients with heart disease or those with prolonged QT intervals, and an ECG may be required. Since it may affect driving or machinery operation abilities, caution is required at the start of treatment or when adjusting dosage. It is advisable not to use this medication during pregnancy or breastfeeding; if it is absolutely necessary, consult a specialist. This medication may interact with specific drugs, so if you are taking other medications, it is crucial to inform your healthcare provider and exercise caution. In case of overdose, serious symptoms such as nausea, vomiting, breathing difficulties, and muscle weakness may occur, and immediate emergency treatment is required, with atropine available as an antidote. When storing, keep it out of reach of children and do not transfer the medication to another container as a safety measure.

Serious side effects

Fainting, bradycardia, heart block, QT interval prolongation, myocardial infarction, heart failure, peptic ulcer, perforated duodenal ulcer, gastrointestinal bleeding, hepatitis, liver dysfunction, jaundice, cerebral seizures (epilepsy, convulsions, etc.), cerebral hemorrhage, cerebrovascular disorders, extrapyramidal disorders (movement disorders, ataxia, motor dysfunction, dystonia, tremors, involuntary movements, gait disturbances, abnormal postures, speech disorders), neuroleptic malignant syndrome (stupor, extreme muscle stiffness)

Mild side effects

• Nausea
• vomiting
• diarrhea
• decreased appetite
• headache
• fatigue
• dizziness
• insomnia
• drowsiness
• rash

This medication should be stored in an airtight container and at room temperature between 1 and 30 degrees Celsius. Proper storage helps maintain the medication's effectiveness over time.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle