Sitagliptin Tablet 25 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

The usual dose is 100 mg once daily whether as monotherapy or in combination. The maximum daily dose is 100 mg. It can be taken regardless of meals. In patients with renal impairment, dosage adjustments are necessary based on kidney function status. - Mild renal impairment (eGFR 60 to < 90): No dosage adjustment needed. - Moderate renal impairment (eGFR 45 to < 60): No dosage adjustment needed. - Moderate renal impairment (e

This medication may cause allergic reactions; if symptoms such as skin rash, difficulty breathing, swelling of the face or neck occur, cease use immediately and consult a physician. Acute pancreatitis, a serious pancreatic inflammation, may occur, so if symptoms such as abdominal pain, vomiting, or loss of appetite appear during use, inform healthcare personnel immediately. It should not be used in patients with Type 1 diabetes or diabetic ketoacidosis, and it should be avoided in patients with allergy to this medication or its components. Patients with impaired kidney function may have increased drug concentrations; therefore, dosage adjustments should be made according to a physician's instructions, and regular kidney function tests are important. When administering this medication, the risk of hypoglycemia may increase; thus, if taken with other hypoglycemic agents like insulin or sulfonylureas, blood sugar changes should be carefully monitored. If symptoms such as severe joint pain or formation of blisters on the skin occur, consult a physician immediately to determine whether to discontinue the medication. Women who are pregnant or breastfeeding are not recommended to use this medication, and safety and efficacy have not been established in children or adolescents under 18 years of age. Elderly patients are at higher risk for impaired kidney function, so kidney function should be periodically examined before and after taking this medication, and dosage should be carefully adjusted. In case of overdose, removal of the drug from the gastrointestinal tract and monitoring of overall health status, including heart condition, are necessary; if needed, some drugs can be removed via hemodialysis. No significant drug interactions have been reported when this medication is used in conjunction with other specific drugs; however, careful monitoring is necessary if digoxin is being taken.

Serious side effects

• Hives
• angioedema
• anaphylaxis
• Stevens-Johnson syndrome
• exfoliative skin disease
• acute pancreatitis
• acute renal failure
• severe joint pain with disabilities
• vulvar pemphigoid
• anaphylaxis

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• dyspepsia
• nausea
• constipation
• myalgia
• limb pain
• back pain

Store this medication in a tightly sealed container to prevent exposure to air or moisture and keep it at room temperature between 1°C and 30°C. Proper storage will help maintain the drug's effectiveness and prevent degradation.

Appearance

Pink, round, biconvex film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP x 3]