Donepezil Hydrochloride 10 mg Tablet (Donepezil Hydrochloride Monohydrate)

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before bedtime. If unusual dreams, nightmares, or insomnia occur, consider taking this medication in the morning. Donepezil's concentration reaches a steady state after 15 days of administration, and the frequency of adverse reactions may be affected by the rate of dose escalation, so administer 5 mg for 4-6 weeks. Assess clinical response during this period.

Child dose

There is no experience using this medication in pediatric patients.

This medication should not be used by women who are allergic to specific ingredients or are pregnant or breastfeeding, and by patients with genetic lactose metabolism disorders. Patients with heart disease or a history of gastrointestinal diseases, asthmatics, or those with a history of specific allergies should be cautious when using this medication. This medication can cause various serious side effects such as slowed heart rate or arrhythmias, worsening of peptic ulcers, liver dysfunction, cerebrovascular issues, and motor disorders, so patients must consult a physician immediately if symptoms occur. Some patients may experience side effects such as nausea, vomiting, diarrhea, dizziness, insomnia, hallucinations, and aggressive behavior, which may require treatment discontinuation or dose adjustment. The effectiveness of this medication may vary depending on the type of dementia, so it should be used under the supervision of a specialist after an accurate diagnosis, and discontinuation should be considered if there is no therapeutic effect. Patients with poor heart health require regular cardiac monitoring, including ECG tests, and those with a history of gastrointestinal disease should carefully monitor for symptom exacerbation. This medication may affect driving or machine operation ability; caution is necessary at the start of treatment or when changing doses. Interactions with other medications may occur, especially when taken with drugs metabolized by the liver or those affecting the heart, so consult a doctor or pharmacist in such cases. It is generally advised that pregnant or breastfeeding women do not use this drug unless absolutely necessary and after consulting a specialist. The safety for children has not been established, so it should not be used in pediatric patients. In case of overdose, serious symptoms such as nausea, vomiting, bradycardia, and respiratory depression may occur, requiring immediate medical attention.

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blistering, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory anomalies accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, sudden severe headache, thunderclap headache, seizures, confusion of consciousness, visual disturbances, paralysis, urination

Mild side effects

• Nausea
• vomiting
• diarrhea
• loss of appetite
• headache
• fatigue
• insomnia
• dizziness
• drowsiness
• rash

This medication should be stored in a tightly sealed container to prevent air exposure and at room temperature between 1 and 30 degrees Celsius. This storage method helps maintain the drug's effectiveness and safety.

Appearance

Yellow round film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle