Entifurin Tablet 10mg (Lafutidine)

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks, although the healing period may vary in some patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks, although the healing period may vary in some patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily at bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks, although the healing period may vary in some patients. 4. Antibiotic combination therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose orally twice daily.

This medication should not be used in patients with known allergies to specific ingredients. Additionally, it contains lactose, so patients with genetic lactose intolerance or related conditions should avoid taking it. Patients with a history of drug allergies, issues with liver or kidney function, or those undergoing dialysis, as well as elderly patients, should exercise special caution when using this medication. This medication can cause serious side effects such as severe allergic reactions, liver dysfunction, and decreased blood cell counts; therefore, if any unusual symptoms occur during use, immediate consultation with a physician is required. Common gastrointestinal symptoms such as constipation, diarrhea, and nausea may occur, along with central nervous system symptoms like headaches or dizziness. Elderly patients and those with reduced kidney function may experience higher drug concentrations, so dosages and intervals should be adjusted and used cautiously. Pregnant women or those who may become pregnant should only take this medication as needed under a doctor's guidance, and nursing mothers are advised to avoid taking it as it may be excreted in breast milk. Safety in children has not yet been established, so usage in pediatric patients is not recommended. This medication may mask the symptoms of malignant tumors; hence, if gastric cancer is suspected, testing must be performed, and administration should be discontinued if malignancy is confirmed. Keep the medication out of reach of children and store it in its original container for safety.

• Shock
• anaphylactic symptoms
• facial pallor
• hypotension
• generalized rash
• dyspnea
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication should be stored in a tightly sealed container to avoid exposure to air or moisture. It is also important to keep the medication at room temperature, between 1°C and 30°C, to maintain its effectiveness for a longer period.

Appearance

White, round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle