Azipet 5 mg Tablets (Donepezil Hydrochloride Monohydrate)

Adult dose

As Donepezil Hydrochloride, administer 5 mg once daily before bedtime. After administering 5 mg for 4-6 weeks, evaluate the clinical response to increase to 10 mg if necessary. When increasing to a daily dose of 10 mg, be cautious with gastrointestinal adverse reactions. Underweight female patients over 85 years old should not exceed 5 mg daily and require close monitoring.

Child dose

There is no experience with the use of this medication in children.

This medication contains Donepezil Hydrochloride Monohydrate as its active ingredient and is used for the improvement of Alzheimer's dementia symptoms. This medication should not be used by certain patients. For example, individuals allergic to this medication or its ingredients, pregnant women or women who may become pregnant, and those with genetic issues such as lactose intolerance should not take it. Patients with heart disease or heart conduction disorders must take this medication cautiously, as it can slow heart rate or cause arrhythmias. Those taking non-steroidal anti-inflammatory drugs or with a history of peptic ulcers should also exercise caution, as this medication can increase gastric acid secretion and enhance gastrointestinal motility, potentially worsening ulcer symptoms. Individuals with a history of asthma or chronic obstructive pulmonary disease should be careful, as bronchoconstriction and increased mucus secretion can worsen symptoms. Patients with extrapyramidal disorders such as Parkinson's disease may experience worsening symptoms when taking this medication, so they should be closely monitored. This medication contains Yellow No. 5 dye, so those allergic to this component should also exercise caution. Taking this medication can lead to a variety of side effects. For example, heart problems may result in fainting or heart block, and gastrointestinal issues may include gastric ulcers or gastrointestinal bleeding, liver dysfunction, cerebral hemorrhage, movement disorders, muscle problems, respiratory distress, pancreatitis, and renal failure. Additionally, psychiatric symptoms such as hallucinations, anxiety, insomnia, depression, and confusion may occur, and cardiovascular issues such as bradycardia, palpitations, and atrial fibrillation may arise. This medication can affect the ability to drive or operate machinery, so special caution is advised during the initial stages of treatment. Pregnant or breastfeeding women should preferably avoid this medication, and if it is essential to use it, they should consult a healthcare professional. This medication can interact with various drugs, so if you are taking other medications, be sure to consult a doctor or pharmacist. In case of overdose, severe symptoms such as nausea, vomiting, bradycardia, hypotension, and respiratory depression may occur, so you should immediately visit a medical institution, and atropine can be used as an antidote. Finally, this medication should be kept out of reach of children, and transferring it to another container is not advisable as it can compromise the quality.

Serious side effects

• Fainting
• bradycardia
• heart block
• QT interval prolongation
• myocardial infarction
• heart failure
• peptic ulcer
• perforated duodenal perforation
• gastrointestinal bleeding
• hepatitis

Mild side effects

• Nausea
• vomiting
• diarrhea
• appetite loss
• headache
• fatigue
• dizziness
• insomnia
• drowsiness
• itching

This medication should be stored in a tightly sealed container to prevent air exposure, and it is best kept at room temperature between 1°C and 30°C. This helps maintain the medication's efficacy and prevent degradation.

Appearance

Yellow round film-coated tablets

Package unit

30 tablets/bottle, 100 tablets/bottle