Crestet Tablet 10/10 mg (Ezetimibe, Rosuvastatin)

Adult dose

This medication is administered once daily irrespective of meals. For primary hypercholesterolemia, it starts with 10/5 mg once daily, and the dose can be adjusted between 10/5 mg to 10/20 mg as needed. After starting treatment or adjusting the dosage, lipid levels in the blood should be checked at intervals of at least 4 weeks to adjust the dosage accordingly. The maximum dose per day is 10/20 mg.

This medication carries the risk of muscle complications, so if any severe muscle pain or weakness symptoms arise, consult a doctor immediately. Particularly in cases of severe infection, hypotension, post-surgery status, trauma, or severe metabolic or endocrine diseases, it may be necessary to temporarily stop or discontinue this medication. Patients allergic to the ingredients of this medication, those with liver disease, or those with muscle diseases should not take it. Additionally, people with severe kidney failure, pregnant or potentially pregnant women, and nursing mothers should not use this medication. Since this medication contains lactose, patients with lactose intolerance should not take it. Alcoholics or patients with a history of liver disease and those at high risk for muscle diseases should take this medication cautiously and require periodic blood tests and muscle condition checks. Side effects such as abnormal liver function, muscle pain, fatigue, headache, dyspepsia, edema, etc., can occur during the course of this medication, so severe symptoms should be reported to a doctor. If severe muscle pain or markedly increased muscle enzyme levels are detected in blood tests, the medication should be stopped immediately and consulting with medical personnel is necessary. This medication may interact with other medications, so it is important to inform your doctor or pharmacist if you are taking any other medications, especially anticoagulants, fibrates, certain antibiotics, and antifungals. This medication should not be used during pregnancy or breastfeeding, and women of childbearing age should use appropriate contraception while taking it. Safety and effectiveness have not been sufficiently established in children and the elderly, hence special caution is required. This medication can affect liver and kidney function, so patients with liver or kidney diseases should regularly undergo tests. There is no specific antidote in case of overdose, so appropriate treatment and supportive therapy based on symptoms should be administered. This medication should be kept out of reach of children and should not be transferred to other containers.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe allergic reactions, severe rash with high fever, blistering, skin peeling, pain in mucous membranes of the mouth/eyes, severe skin adverse reactions, shortness of breath or difficulty breathing, asthma attack, respiratory distress accompanied by cough and fever, disruption of liver function (jaundice), sudden and severe headache,

Mild side effects

Headache, dizziness, nasopharyngitis, dyspepsia, muscle pain, chest discomfort, dry mouth, increased levels of blood lactate dehydrogenase, pruritus, urticaria, rash, constipation, nausea, abdominal pain, diarrhea, loss of appetite, abdominal bloating, weakness, joint pain, fatigue, numbness, paresthesia, vomiting, epigastric discomfort, belching, gastrointestinal disorders, gastroesophageal reflux disease, tongue disease, diabetes, depression, cough, thrombocytopenia, alopecia, nasal congestion, phlegm,

This medication can be sensitive to air and moisture, so it should be stored in a tightly sealed container. It is advisable to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance

Yellow oblong film-coated tablets

Package unit

30 tablets/box [10 tablets/PTP×3]