Crestzet Tablets 10/20 mg (Ezetimibe, Rosuvastatin)

Adult dose

This medication is taken once daily, regardless of meals. The dosage range is from 10/5 mg to 10/20 mg per day. A starting dose of 10/5 mg per day is recommended. For patients requiring a greater reduction of LDL-cholesterol, the dosage may be adjusted accordingly. After initiation of treatment or adjustment of the dosage, blood lipid levels should be checked at intervals of at least four weeks; the daily maximum dosage can be increased to 10/20 mg.

This medication has the risk of causing serious muscle problems, so if sudden muscle pain or weakness occurs, you should immediately inform your doctor. In particular, it may be necessary to discontinue or temporarily halt the use of this medication in cases of severe infection, hypotension, major surgery or trauma, hypothyroidism, or renal function impairment. Patients allergic to any ingredients contained in this medication, those with severely impaired liver function, patients with muscular diseases, and women who are pregnant or breastfeeding should not take this medication. Moreover, the risk of muscle damage may increase when taken with certain medications, so if you are on other medications, be sure to inform your doctor or pharmacist. During treatment with this medication, regular liver function and muscle-related tests must be conducted, and if any abnormal symptoms appear, consult healthcare personnel immediately. Elderly patients or those with impaired renal function should exercise caution when using this medication. Women of childbearing potential should use appropriate contraception during treatment and must immediately discontinue the medication if pregnancy is confirmed. Safety has not been adequately established in children and adolescents, so it is not recommended for this age group. This medication should be administered cautiously to individuals with a history of excessive alcohol consumption or liver disease, and treatment should be immediately halted if symptoms indicating liver or muscle effects occur. Finally, caution should be exercised when driving or operating machinery as symptoms such as dizziness may occur.

Serious side effects

Hives, severe edema (swelling), chest tightness, difficulty breathing, cold sweats, paleness, severe rash accompanied by fever, blisters, skin peeling, mouth/eye mucosal pain, severe skin abnormal reactions, difficulty breathing or shortness of breath, asthma attack, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), profound lethargy, liver abnormalities (jaundice), sudden and severe headaches, thunderclap headaches, seizures.

Mild side effects

Nasal pharyngitis, dyspepsia, headache, muscle pain, dry mouth, elevated liver enzymes, abnormalities in liver function tests, increased blood lactate dehydrogenase levels, pruritus, chest discomfort, upper respiratory tract infection, increased blood sugar, elevated CPK levels, dizziness, drowsiness, cough, cold sweats, dermatitis, skin burning sensation, skin disorders, alopecia, nausea, abdominal pain, diarrhea, loss of appetite, abdominal bloating, syncope, generalized pain, muscle cramps, gout, erectile dysfunction, urinary issues.

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is also important to store the medication at a cool room temperature, specifically between 1°C and 30°C. This will help maintain the medication's efficacy over time.

Appearance

Pink oval film-coated tablets

Package unit

30 tablets/box [10/PTP×3]