Genupharm Pioglitazone Tablets (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once daily, regardless of meals. It can be started at 15 mg once daily as monotherapy, and if the effect is insufficient, the dose can be increased to 30 mg once daily. In combination therapy, it is administered 15 mg once daily along with sulfonylureas, metformin, or insulin, with a maximum recommended dose not to exceed 30 mg once daily.

Child dose

There is no experience in using this medication in children under 18 years of age, so its administration is not recommended.

This medication is used for the treatment of type 2 diabetes. It may cause or worsen congestive heart failure in some patients, so when starting treatment or increasing the dose, symptoms of heart failure such as rapid weight gain, shortness of breath, and leg swelling should be carefully monitored. It is advisable to avoid this medication in patients with heart failure, and if symptoms of heart failure occur, medical consultation should be sought immediately. When administered with insulin, this medication may lead to fluid retention, increasing the risk of heart failure, so caution is required in such cases. This medication should not be used in patients with a history of bladder cancer or active bladder cancer, and if hematuria or urinary disorders occur during treatment, healthcare providers should be notified immediately. Patients with impaired liver function or severe renal impairment should also use this medication with caution. When used in conjunction with other diabetes medications that pose a risk of hypoglycemia, symptoms of hypoglycemia may occur, so understanding hypoglycemia symptoms and management is essential. Side effects such as edema, weight gain, headaches, upper respiratory infections, myalgia, may occur, and if abnormal symptoms persist, consultation with a doctor is necessary. Women who are pregnant or may become pregnant must consult a healthcare provider before taking this medication, and special caution is required for nursing mothers. This medication is not recommended for children and adolescents under 18 years of age, as safety and efficacy have not been established. Elderly patients should be closely monitored during administration, especially those aged 75 years and older. Regular monitoring of blood glucose and liver function tests is required while taking this medication, and any sudden weight gain or symptoms of edema or shortness of breath should be reported to a physician immediately. Finally, this medication should be stored out of reach of children, and kept in its original container to maintain quality.

Serious side effects

Congestive heart failure, symptoms and signs of heart failure (including excessive and rapid weight changes, dyspnea, edema), severe edema, heart function failure, bladder cancer, hepatic abnormalities (jaundice and liver dysfunction), fatal and non-fatal hepatic failure, severe neurological symptoms (headache, seizures, altered consciousness, visual disturbances, paralysis), severe heart failure, hospitalization due to hypoglycemia, acute myocardial infarction, stroke, cardiovascular mortality, pneumonia, asthma

Mild side effects

• Upper respiratory infection
• headache
• sinusitis
• myalgia
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infection
• low back pain

This medication should be stored in a container that can block light and air, and should be kept away from humid places. The ideal storage temperature is between 15 and 30 degrees Celsius, and it is advisable to store it at room temperature around 25 degrees Celsius.

Appearance

White round tablet

Package unit

Bottle - 30 tablets/bottle, Bottle - 100 tablets/bottle