Posizine 10 mg (Dapagliflozin)

Adult dose

The recommended dosage for this medication is 10 mg once daily for both monotherapy and additional combination therapy with insulin or other glucose-lowering agents. This medication can be taken at any time of the day orally regardless of food intake, and the tablets should be swallowed whole.

Child dose

The efficacy and safety of dapagliflozin in children under 18 years of age have not been established.

This medication should not be administered to certain patients. For example, individuals allergic to the components or excipients of this medication, patients with type 1 diabetes, patients with diabetic ketoacidosis, and those with genetic conditions such as lactose intolerance should not use it. Additionally, patients undergoing dialysis should not take this medication. This medication should be used cautiously in patients with reduced fluid volume or poor kidney function, as it may lower blood pressure or temporarily alter blood creatinine levels, putting stress on the kidneys. Special caution is required for the elderly or those taking diuretics, and fluid status and kidney function should be carefully monitored before and after administration. Various side effects may occur while taking this medication. Commonly, genital infections, urinary tract infections, hypoglycemia, reduced fluid volume, and diabetic ketoacidosis may occur. Genital and urinary tract infections may occur more frequently in women, and treatment is required immediately upon symptom onset. Hypoglycemia may occur more frequently when used with medications such as insulin or sulfonylureas, so caution is advised. This medication is not recommended for patients with severely impaired liver function, and those at risk of fluid volume reduction or hypotension should be particularly cautious. Additionally, serious metabolic disturbances such as ketoacidosis may occur, necessitating immediate consultation with a healthcare provider if symptoms arise. This medication may interact with other drugs, so those taking diuretics, insulin, or sulfonylureas should consult their doctor. It is advisable for pregnant or breastfeeding women not to use this medication. Regular blood sugar tests and kidney function tests are needed during treatment, as this medication can affect blood sugar control. Although it does not significantly impact driving or operating machinery, caution should be taken for potential hypoglycemic symptoms. The safety and efficacy of this medication in children have not been established, so it is not to be used in this population. In case of overdose, contact a medical facility immediately for appropriate treatment, as this medication may not be rapidly eliminated and may require professional management. Finally, this medication should be stored out of reach of children and kept in its original container for safety.

Serious side effects

Necrotizing fasciitis of the perineum (Fournier's gangrene), diabetic ketoacidosis, reduced fluid volume (including dehydration, hypovolemia, hypotension), acute kidney injury and renal dysfunction, urinary tract sepsis and pyelonephritis, anaphylaxis, hives, severe swelling, chest tightness, difficulty breathing, cold sweats, pallor, severe rash along with high fever, blisters, skin peeling, oral/ocular mucosal pain, difficulty breathing or shortness of breath, asthma attacks, cough

Mild side effects

Vulvovaginitis, balanitis and related genital infections, urinary tract infections, hypoglycemia, dizziness, constipation, dry mouth, back pain, dysuria, polyuria, nocturia, genital itching, increased hematocrit, elevated serum creatinine levels at the beginning of treatment, dyslipidemia, weight loss, chest pain, weakness, pain, itching, hives, cold sweats, cough, difficulty breathing, palpitations, insomnia, fatty liver, gallbladder polyps, vertigo, allergic rhinitis, asthma,

This medication should be stored in a tightly closed container to avoid exposure to air or moisture, at a safe temperature between 1 degree and 30 degrees Celsius. Proper storage will help maintain the efficacy of the medication and prevent deterioration.

Appearance

A yellow, biconvex diamond-shaped film-coated tablet

Package unit

100 tablets/bottle, 8 tablets/box [8 tablets/Alu-Alu]