Loperakim Capsule (Loperamide Hydrochloride)

Adult dose

Acute Diarrhea: The initial dose is 4 mg of loperamide hydrochloride orally, with maintenance doses of 2 mg each time there is a loose stool. The daily regular dose is 6-8 mg, with a maximum daily dose of 16 mg. Chronic Diarrhea: The initial dose is 4 mg of loperamide hydrochloride orally, with 2 mg administered each time there is a loose stool until the diarrhea is resolved. After that, the dosage should be reduced individually as needed, and the optimal daily dose should be divided into one or two administrations. Typically, the maintenance dose is 2-6 mg per day, with a maximum dose of 16 mg.

Child dose

Acute Diarrhea: The initial dose is 2 mg of loperamide hydrochloride orally, with a maintenance dose of 2 mg given each time there is a loose stool. The maximum daily dose is 6 mg. Adjust according to age and symptoms.

This medication should not be used in infants under 24 months, children with chronic diarrhea, or patients with bacterial diarrhea presenting with bloody stools and high fever. Additionally, it should not be administered to patients with acute ulcerative colitis, patients with pseudomembranous colitis from broad-spectrum antibiotic administration, or patients with severe intestinal diseases such as intestinal obstruction or megacolon. If symptoms such as abdominal distension, constipation, or intestinal obstruction occur, use should be discontinued immediately, and patients who have had allergic reactions to this medication should not use it. This medication contains lactose, so it should not be administered to patients with lactose intolerance or related genetic disorders. Patients with impaired liver function should use this medication cautiously and should be closely monitored for central nervous system side effects. This medication does not directly treat the cause of diarrhea but relieves symptoms, so if acute diarrhea does not improve within 48 hours or chronic diarrhea does not improve within 10 days, use should be discontinued and a specialist should be consulted. Fluid and electrolyte loss may occur due to diarrhea, so proper fluid and electrolyte replenishment is especially necessary for children. During the use of this medication, symptoms such as fatigue, dizziness, and drowsiness may occur, so caution is required when driving or operating machinery. In early pregnancy, the benefits and risks of using this medication should be carefully considered prior to administration, and while breastfeeding, it is not recommended as the medication may be excreted in small amounts in breast milk. Special care is needed for children, and children aged 24 months to under 7 years should take it strictly according to the instruction of a specialist. The elderly may have decreased physical functions; hence, careful dose adjustment is recommended. In cases of overdose, serious side effects such as central nervous system depression, respiratory depression, and cardiac arrhythmias may occur, and the prescribed dosage should not be exceeded. In case of overdose, seek medical attention immediately. This medication may interact with other drugs, so it is important to consult a specialist if other medications are being taken.

Serious side effects

• Urticaria
• angioedema
• Stevens-Johnson syndrome
• toxic epidermal necrolysis
• anaphylaxis
• anaphylactic shock
• intestinal obstruction
• toxic megacolon
• acute pancreatitis
• urinary retention

Mild side effects

• Dry mouth
• abdominal distension
• abdominal cramping
• acute pain
• nausea
• vomiting
• headache
• constipation
• dizziness
• drowsiness

This medication should be stored in a tightly sealed container to protect it from air and moisture. The storage temperature should ideally be maintained at room temperature between 15 degrees and 25 degrees.

Appearance

A capsule with white contents, consisting of a white shell.

Package unit

1,000 capsules per bottle