Rosuemjet Tablet 10/10 mg (Ezetimibe, Rosuvastatin)

Adult dose

This drug is administered once daily regardless of meals. For primary hypercholesterolemia, an initial dose of 10/5 mg once daily is recommended. For patients requiring a greater reduction in LDL cholesterol, the dose may be adjusted, and it may be increased up to a maximum of 10/20 mg per day. Blood lipid levels should be checked at intervals of more than 4 weeks after starting treatment or after dose adjustments to adjust the dosage accordingly.

This drug can cause a rare side effect called rhabdomyolysis, which can lead to serious problems with muscles. Since it may rapidly worsen kidney function, patients should stop taking the drug immediately and consult a doctor if they experience severe muscle pain or weakness. Patients should undergo liver function tests before taking this drug, and it should not be administered if there are abnormal symptoms or persistently high liver enzyme levels. Regular liver function tests should be conducted if liver abnormalities are suspected, and the medication should be stopped if liver enzymes rise significantly. Patients consuming large amounts of alcohol or with a history of liver disease, those with severe kidney dysfunction, and patients with muscle disorders should take this drug with caution. In particular, patients with poor kidney function or hypothyroidism are at higher risk of muscle problems and should be monitored closely. This drug should not be given to pregnant or potentially pregnant women, or nursing mothers, and women of childbearing age should ensure appropriate contraception while taking it. During treatment, if symptoms such as muscle pain, cramping, weakness, or fever arise, immediate medical attention should be sought and blood tests conducted to assess for muscle damage if necessary. There may be interactions with other medications, so all current medications should be disclosed to healthcare professionals, especially when taken with cyclosporine, fibric acid derivatives, certain antifungals, and antivirals. Symptoms such as dizziness or headache may occur, so caution is advised during driving or operating machinery. This drug is generally not recommended for children as safety and efficacy have not been established. In case of overdose, there is no specific antidote available; treatment should be symptomatic and supportive, and liver function and muscle damage should be closely monitored. This drug contains lactose, so it should not be given to patients with lactose intolerance, and it should be discontinued immediately if serious skin reactions occur.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blistering, skin peeling, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attack, respiratory difficulties accompanied by cough and fever, jaundice (yellowing of the skin or eyes), extreme lethargy throughout the body, sudden and severe headache, thunderclap headache, seizures, confusion, vision problems, paralysis, difficult urination

Mild side effects

• Headache
• arthralgia
• myalgia
• pharyngitis
• dizziness
• fatigue
• nausea
• abdominal pain
• constipation
• diarrhea

This drug should be stored in a sealed container to protect it from air and moisture, and storage temperatures should be maintained between 1 to 30 degrees Celsius. Proper storage will maintain the drug's efficacy for a longer time.

Appearance

Pale pink, oblong film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP X 3]