KVAJET Tablet 10/20 mg

Adult dose

This medication is taken once daily without regard to meals. For primary hypercholesterolemia, an initial dose of 10/5 mg once daily is recommended. For patients requiring further reduction of LDL cholesterol, the dosage may be adjusted up to a maximum of 10/20 mg daily. Following the initiation of therapy or dosage adjustment, lipid levels should be checked at intervals of four weeks or longer.

This medication may cause a rare serious side effect known as rhabdomyolysis, which can lead to rapid deterioration of kidney function; therefore, patients should inform their healthcare provider immediately if they experience severe muscle pain or weakness. This medication should not be used in patients with allergies to its ingredients, severe liver dysfunction, myopathy, significantly impaired kidney function, pregnant women or women who may become pregnant, and breastfeeding mothers. Additionally, caution should be exercised in patients with certain genetic disorders or those with a history of alcoholism, hypothyroidism, elderly patients, and when used in combination with other lipid-lowering agents due to an increased risk of muscle problems. Prior to administration, liver function tests and muscle enzyme tests should be performed, and regular monitoring should continue during treatment. Patients should immediately report any symptoms of muscle pain, fatigue, or fever to their healthcare provider for testing. This medication can cause liver dysfunction, so it should be discontinued immediately if signs of liver damage appear, and extra caution is warranted for patients with a history of excessive alcohol use or liver disease. Pregnant or breastfeeding women should not take this medication, and women of childbearing age should employ appropriate contraception. Because the safety and efficacy for children and elderly individuals have not been sufficiently confirmed, caution is advised for their use. As this medication can interact with other drugs, patients should inform their healthcare provider or pharmacist of any medications they are currently taking, particularly when used with anticoagulants, certain antibiotics, antifungal agents, and immunosuppressants. Patients should be cautious during driving or operating machinery, as dizziness and other symptoms may occur while taking this medication.

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, peeling skin, pain in oral/ocular mucous membranes, shortness of breath or breathing difficulty, asthmatic attacks, respiratory distress accompanied by cough and fever, yellowing of the skin or eyes (jaundice), marked lethargy, sudden and severe headache, lightning headache, seizures, confusion, visual disturbances, paralysis, urination changes

Mild side effects

• Pharyngitis
• arthralgia
• headache
• dizziness
• upper respiratory infection
• itching
• rash
• pruritus
• constipation
• nausea

This medication should be stored in a tightly closed container to avoid exposure to air or moisture. It is important to maintain storage temperatures between 1 to 30 degrees Celsius.

Appearance

White to almost white round film-coated tablets

Package unit

30 tablets/box (10 tablets/PTPX3), 30 tablets/bottle, 100 tablets/bottle