Sitagliptin Tablet 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered once daily at a dosage of 100 mg, whether as monotherapy or in combination therapy, with a maximum daily dosage of 100 mg. This medication can be taken regardless of meals. In patients with renal impairment, dosage adjustments are necessary based on renal function. - In patients with mild renal impairment (eGFR 60–90 mL/min/1.73 m2), no dosage adjustment is required. - In patients with moderate renal impairment (eGFR 45–60 mL/min/

Rarely, this medication can cause serious allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur, discontinue use immediately and consult a physician. This medication can cause acute pancreatitis, which is an inflammation of the pancreas, so if severe abdominal pain, nausea, or vomiting occurs, immediate medical attention is required. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and it should not be administered to those who have allergies to the drug or its components. In patients with impaired renal function, dosage adjustment is necessary, so individuals with kidney disease should inform their healthcare provider. While taking this medication, upper respiratory tract infections, headaches, dyspepsia, diarrhea, etc., may occur, and there is a possibility of hypoglycemic symptoms, so caution is warranted. Especially when taken in combination with insulin or sulfonylureas, the risk of hypoglycemia increases, so blood glucose levels should be checked frequently, and dosage adjustments may be needed. This medication has been reported to have rare side effects such as arthralgia or skin blistering; if such symptoms occur, inform a physician immediately. Use of this medication during pregnancy or lactation is not recommended, and safety has not been established in children under 18 years of age. Elderly patients may have a higher risk of renal function decline, so regular kidney function tests are advisable before and after taking this medication. In cases of overdose, gastrointestinal removal of the drug and appropriate monitoring such as ECG may be necessary, and some of the drug may be removed via hemodialysis. This medication generally has minimal drug interactions when combined with other hypoglycemic agents, but caution is needed when combined with certain medications, so it should be discussed with a physician or pharmacist.

Serious side effects

• Urticaria
• severe swelling (edema)
• anaphylaxis
• angioedema
• severe allergic reactions
• severe rashes
• blisters
• skin peeling
• pain of oral/ocular mucosa
• Stevens-Johnson syndrome

Mild side effects

• Rhinitis
• upper respiratory tract infections
• headaches
• constipation
• vomiting
• myalgia
• limb pain
• back pain
• pruritus
• thrombocytopenia

Store this medication in an airtight container to prevent air exposure, maintaining a storage temperature between 1 to 30 degrees Celsius. Proper storage will help retain the drug's efficacy.

Appearance

Pale orange, round, convex film-coated tablet

Package unit

28 tablets) 14 tablets/PPT (x2), 30 tablets) 10 tablets/PPT (x3)