Celebrex Capsule 100 mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered regardless of meals. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis Take 100 mg or 200 mg of celecoxib per dose, twice daily. 3. Ankylosing spondylitis (AS) Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg daily. If no effect is observed after 6 weeks of treatment with 400 mg daily, another treatment should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment For patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may cause gastrointestinal bleeding if taken by individuals who regularly consume large amounts of alcohol daily, so it is essential to consult a doctor or pharmacist. This medication may increase the risk of cardiovascular diseases such as heart attack or stroke, so it should only be used at the minimum effective dose and for the shortest duration. Immediate reporting of any cardiovascular symptoms is necessary. Due to the risk of ulcers or bleeding in the gastrointestinal tract, if gastrointestinal disturbance symptoms occur, immediate consultation with a doctor is advised, especially for older individuals who should be more cautious. This medication should not be used in individuals with specific allergies, severely impaired liver or kidney function, active gastric ulcers, heart diseases, or in pregnant or breastfeeding women. Patients with impaired liver or kidney function, asthma, hypertension, heart failure, or diabetes need to exercise special caution while taking this medication. During treatment with this medication, various side effects such as headaches, dizziness, dyspepsia, vomiting, skin rashes, edema, and hypertension may occur; if symptoms are severe, a doctor should be notified. This medication is metabolized in the liver, thus dosage adjustments may be needed when taken with other drugs that affect liver function. Women who are pregnant, planning to become pregnant, or breastfeeding should not take this medication and must discontinue it immediately if pregnancy is confirmed during treatment. Elderly patients are likely to have impaired kidney and liver function, requiring closer observation when administering this medication. If this medication is taken for an extended period, regular blood tests and assessments of liver and kidney function should be conducted, and its use should be stopped immediately if any abnormal signs appear. In case of overdose, symptoms may include vomiting, drowsiness, and gastrointestinal bleeding; there is no specific antidote, so appropriate treatment should be provided according to symptoms. Keep this medication out of reach of children and do not transfer it to another container.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental diseases, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, liver enzyme elevation, itching, rash, urticaria, petechiae, angioedema, alopecia, blistering dermatitis, peripheral edema, facial swelling, influenza-like illness, injury, taste disturbance, albuminuria, cystitis, hematuria, dysuria, frequent urination, kidney stones, urinary incontinence, urinary tract infection, vision blurriness, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, elevated β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, headache, leg cramps, muscle tension, sensory disturbance, migraine, neuralgia, neuropathy, sensory anomalies, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergic exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylaxis-like reaction, angioedema, insomnia, decreased appetite, increased appetite, depression, neuroexcitation, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, shingles, wound infection, gingivitis, herpes simplex, herpes zoster, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast tenderness, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver function abnormalities, elevated ALT, elevated AST, increased γ-GTP, elevated ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, hepatic necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, increased NPN, increased creatinine, elevated alkaline phosphatase, weight gain, decreased appetite, elevated LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical tension, synovitis, tendinitis, myositis, fractures, tendon rupture, pain in the back, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleeds, thrombocytopenic purpura, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, vasculitis, contact dermatitis, injection site reactions, skin nodules, vision blurriness, cataracts, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased blood creatinine, elevated β2-microglobulin, increased NAG, positive urinary hematuria, positive urinary protein, renal dysfunction, acute renal failure, interstitial nephritis, menstrual disorders, chest pain, anaphylaxis reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, conjunctivitis, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, photosensitivity reactions, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash, acute generalized exanthematous pustulosis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, microscopic lesion glomerulonephritis, female infertility

Store this medication in a tightly sealed container to prevent air and moisture infiltration, preferably in a cool place between 15 to 30 degrees Celsius. Maintaining the proper storage temperature ensures the medication's efficacy and safety.

Appearance

A white capsule filled with a white to pale yellow powder with blue stripes on the top and bottom.

Package unit

Bottle - 30 capsules/bottle, Bottle - 100 capsules/bottle