Sitagliptin Alpha Tablets 50 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered as a single daily dose of 100 mg, with a maximum daily dose of 100 mg when used alone or in combination therapy. It can be taken regardless of meals. In patients with renal impairment, dosage adjustments are required, reducing to 50 mg or 25 mg based on glomerular filtration rate. - Dosage adjustments are not necessary for mild and moderate renal impairment (glomerular filtration rate between 45 and 90 mL/min).

This medication may cause severe allergic reactions after administration; therefore, if symptoms such as skin rash or difficulty breathing occur, use should be stopped immediately and consultation with a physician is advised. This medication may cause serious inflammation of the pancreas known as pancreatitis, so if symptoms such as abdominal pain, vomiting, or fever appear, it is crucial to inform medical personnel immediately. It should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in patients who have had allergic reactions to this medication or its components. In patients with impaired kidney function, dosage adjustments are necessary, so regular kidney function tests should be conducted. When used with other blood sugar-lowering agents, especially insulin or sulfonylureas, there is an increased risk of hypoglycemia, so blood sugar levels must be monitored carefully. This medication may induce severe joint pain or skin diseases such as bullous pemphigoid, so if such symptoms occur, medical advice should be sought immediately. Women who are pregnant or breastfeeding are advised to avoid using this medication, and its safety and efficacy have not been established in children or adolescents under 18. Elderly patients may have diminished kidney function, necessitating dosage adjustments and regular monitoring of kidney function. In cases of overdose, standard treatment protocols apply, and blood dialysis may remove some of this medication, so dialysis treatment should be considered if needed. This medication has relatively few interactions with other drugs, but should be discussed with a physician when taken alongside specific medications.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylaxis, exfoliative skin disorders including Stevens-Johnson syndrome, acute pancreatitis, worsening renal function (including acute renal failure), severe and debilitating joint pain, bullous pemphigoid, severe hypoglycemia, pneumonia, diabetic complications, metabolic acidosis, falls, cardiac arrest

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• diarrhea
• nausea
• constipation
• myalgia
• limb pain
• back pain
• pruritus

This medication should be stored in a sealed container to prevent exposure to air and should be kept at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness over time.

Appearance

Pale yellowish-pink, round, biconvex film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP×3]