Januvia 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered at a dosage of 100 mg once daily in monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with kidney impairment, dosage adjustments are necessary based on kidney function. - Mild kidney impairment (eGFR 60 or above but less than 90): No dosage adjustment needed - Moderate kidney impairment (eGFR 45 or above but less than 60): No dosage adjustment needed - Moderate kidney impairment

This medication may cause severe allergic reactions, so if skin rash, difficulty breathing, or swelling of the face or lips occurs after use, discontinue immediately and consult a doctor. This medication can cause serious inflammation of the pancreas called pancreatitis, so if abdominal pain, vomiting, or loss of appetite appears during use, inform healthcare professionals immediately. Patients with type 1 diabetes or diabetic ketoacidosis should not take this medication. Patients with reduced kidney function should have their dosage adjusted, so renal function tests should be performed before use, and follow the doctor's instructions. When taken with insulin or sulfonylureas, care should be taken to monitor blood sugar levels closely due to the risk of low blood sugar, and dosage adjustments of other medications may be necessary. During treatment with this medication, side effects such as headache, upper respiratory tract infections, nasopharyngitis, diarrhea, nausea, may occur, and if symptoms are severe, consult a doctor. Severe joint pain or skin blistering similar to bullous pemphigoid may occur, so if such symptoms occur, inform a doctor immediately. Pregnant or breastfeeding women should avoid taking this medication, and safety and efficacy in pediatric patients under 18 years of age have not been established. Older adults are encouraged to regularly monitor kidney function before and during treatment due to the potential decline in kidney function. In case of overdose, seek medical attention immediately for appropriate treatment; some medication can be removed via blood dialysis. There are few interactions with other medications, but consult a doctor or pharmacist when used in combination with certain medications.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, rash, cutaneous vasculitis, Stevens-Johnson syndrome, severe dermatologic adverse reactions (including exfoliative dermatitis), acute pancreatitis, acute renal failure, severe joint pain with disability, bullous pemphigoid, rhabdomyolysis, elevated liver enzymes, jaundice (liver issues), pneumonia, diabetic complications, metabolic acidosis, cardiac arrest

Mild side effects

• Nasopharyngitis
• upper respiratory tract infection
• headache
• diarrhea
• nausea
• constipation
• muscle pain
• limb pain
• back pain
• pruritus

This medication should be stored in an airtight container to prevent air ingress and kept at room temperature between 1 degree and 30 degrees Celsius. Proper storage helps maintain the medication's efficacy.

Appearance

Light orange, round, double-convex film-coated tablet

Package unit

30 tablets (10 tablets/PTP X 3)