Anyvia Tablets 100 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered as a single daily dose of sitagliptin at 100 mg either alone or in combination therapy, with a maximum daily dose of 100 mg. This medication can be taken regardless of meals. In patients with moderate renal impairment (glomerular filtration rate [eGFR] ≥ 30 mL/min/1.73 m2 and < 45 mL/min/1.73 m2), a daily dose of 50 mg is administered.

This medication is an antidiabetic agent made with the ingredient sitagliptin. First, caution should be taken as serious allergic reactions may occur while taking this medication, including anaphylaxis, angioedema, and severe skin rashes or exfoliative skin disorders. If such symptoms occur, stop taking the medication immediately and visit a hospital. Second, there is a risk of pancreatitis (inflammation of the pancreas). If symptoms such as abdominal pain, vomiting, or severe abdominal discomfort occur after taking this medication, consult a doctor immediately. Third, this medication is not used in patients with type 1 diabetes or diabetic ketoacidosis. Fourth, patients with impaired kidney function may need dose adjustments, and regular kidney function tests are important. Fifth, when used in conjunction with insulin or sulfonylurea medications, there may be an increased risk of hypoglycemia, so careful monitoring of blood sugar changes is necessary. Sixth, long-term use may result in side effects such as headache, upper respiratory infection, nasopharyngitis, diarrhea, nausea, and persistent symptoms should be discussed with a doctor. Seventh, it is recommended that pregnant or breastfeeding women avoid using this medication. Eighth, in case of overdose, visit a medical institution immediately for appropriate treatment and monitoring. Blood dialysis may be considered if necessary. Finally, while this medication is known not to increase cardiovascular disease risk even with long-term use, elderly patients or those with impaired kidney function should be more cautious.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, Stevens-Johnson syndrome including exfoliative skin disorders, severe hypersensitivity reactions, acute pancreatitis, acute kidney failure, severe and disabling arthralgia, bullous pemphigoid, severe hypoglycemia, pneumonia, diabetic complications, metabolic acidosis, cardiac arrest

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• myalgia
• limb pain

This medication should be stored in a tightly sealed container to prevent air exposure, and it is best to store it at room temperature between 1 and 30 degrees Celsius. This will help maintain the medication's effectiveness.

Appearance

Light orange, round, biconvex film-coated tablet

Package unit

28 tablets) 14 tablets/PTP (x2), 30 tablets) 10 tablets/PTP (x3)