Medication info
Cojarotane Plus F Tablet

Cojarotane Plus F Tablet

Prescription medicationTablet경구
Ingredient · strength
Losartan Potassium›100mg / 1 tabletHydrochlorothiazide›25mg / 1 tablet
Manufacturer / importer
(주)보령바이오파마
Appearance
Pale yellow oval film-coated tablet
Packaging
Bottle - 30 tablets/bottle
Approval status
Active

MFDS item code 202004054 · Approved 2020.05.29

Summary

Main use
Improvement in blood pressure control when single therapy for hypertension is insufficient
Who takes it
Adults · Children
Adult dose
The usual dose is 1 tablet of Losartan potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily. Doses exceeding Losartan potassium 100 mg/Hydrochlorothiazide 25 mg per day are not desirable. Patients whose blood pressure is not controlled with single therapy of Losartan or Hydrochlorothiazide should start with 1 tablet of Losartan potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily, if after 3 weeks still
Child dose
There is no experience with the use in children and adolescents (under 18 years), so it should not be administered.

Ingredients

Manufacturer
(주)보령바이오파마

Efficacy & effects

Improvement in blood pressure control when single therapy for hypertension is insufficient

  • Hypertension
View approved original text

This medication is used in patients with hypertension who have difficulty controlling blood pressure with monotherapy.

How to take

Adult dose

The usual dose is 1 tablet of Losartan potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily. Doses exceeding Losartan potassium 100 mg/Hydrochlorothiazide 25 mg per day are not desirable. Patients whose blood pressure is not controlled with single therapy of Losartan or Hydrochlorothiazide should start with 1 tablet of Losartan potassium 50 mg/Hydrochlorothiazide 12.5 mg once daily, if after 3 weeks still

Child dose

There is no experience with the use in children and adolescents (under 18 years), so it should not be administered.

Precautions

This medication can cause serious harm to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters, so it should be discontinued immediately upon confirmation of pregnancy. It should not be administered to patients with allergies to this medication or its components, those with severely impaired kidney function, specific electrolyte imbalances, or certain genetic lactase deficiency. Patients with hypotension, kidney or liver dysfunction, abnormal serum potassium levels, the elderly, or those with a history of diabetes or gout should use this medication with caution. Since this drug has a blood pressure-lowering effect, dizziness or drowsiness may occur in the initial stages of treatment, so caution is advised when driving or operating machinery. Electrolyte levels and kidney function should be regularly monitored through blood tests, and it is recommended to avoid concurrent use with potassium supplements or potassium-containing medications. This medication may make the skin more sensitive to sunlight, so sun exposure should be minimized, and if any abnormalities occur on the skin, a doctor should be consulted immediately. Side effects such as cough, headache, abdominal pain, muscle pain, and rash may occur, but most are mild and transient. Women who are pregnant or planning to become pregnant should consult a doctor, and it is important to consult a specialist before using it while breastfeeding. This medication lacks sufficient experience for use in children and adolescents and is not recommended for them. In cases of overdose, hypotension and arrhythmias may occur, so immediate medical attention is required, and treatment should be conducted appropriately according to the symptoms. Store this medication in its original packaging in a place out of reach of children.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blisters, skin peeling, pain in oral/ocular mucosa, dyspnea or difficulty breathing, asthma attack, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), profound lethargy, sudden and severe headache, thunderclap headache, seizures, altered consciousness, visual disturbances, paralysis, urination

Mild side effects

Abdominal pain, edema/infusion, palpitations, back pain, dizziness, cough, sinusitis, upper respiratory tract infection, weakness/fatigue, diarrhea, nausea, headache, bronchitis, pharyngitis, chest pain, facial swelling, fever, orthostatic hypotension, syncope, angina, arrhythmias (atrial fibrillation, sinus bradycardia, tachycardia, ventricular tachycardia, ventricular fibrillation), cerebrovascular accident, hypotension, myocardial infarction, secondary atrioventricular block, anorexia, constipation, toothache, dry mouth, dyspepsia, flatulence, gastritis, vomiting

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container that blocks light, and it is preferable to store it at a temperature between 1°C and 30°C at room temperature. Storing it this way can help maintain the effectiveness of the medication.

Appearance and packaging

Appearance

Pale yellow oval film-coated tablet

Package unit

Bottle - 30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.