Acyta 100 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered at a dosage of 100 mg once daily for both monotherapy and combination therapy, with a maximum daily dose of 100 mg. It can be taken without regard to meals. Dose adjustments may be required based on renal function. For mild or moderate renal impairment (eGFR 45 to less than 90), dose adjustments are not required. For moderate renal impairment (eGFR 30 to less than 45), administer 50 mg once daily. For severe renal impairment (eGFR less than 30) or for patients requiring hemodialysis or peritoneal dialysis (ESRD), administer 25 mg once daily.

This medication may cause severe allergic reactions, so if symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult a physician. This medication may cause inflammation of the pancreas, so if symptoms such as abdominal pain or vomiting occur, promptly inform a healthcare professional. Patients with type 1 diabetes or those who have had allergic reactions to this medication should not take it. Patients with impaired renal function may require dose adjustments and should undergo regular kidney function tests. During treatment with this medication, side effects such as cold symptoms, headache, or gastrointestinal discomfort may occur; if symptoms are severe, consult a physician. Careful monitoring of blood sugar levels is necessary, especially when taking other hypoglycemic agents or insulin, as the risk of hypoglycemia may increase and dosage adjustments may be needed. This medication is not recommended for women who are pregnant or breastfeeding, and its safety has not been established in children under 18 years of age. Elderly patients may have reduced kidney function, so dose adjustments and monitoring of renal function are necessary. In case of overdose, gastrointestinal decontamination may be performed, and monitoring of conditions such as electrocardiograms may be necessary; dialysis treatment may need to be considered if required. This medication has minimal major interactions with other medications, but caution may be needed when used in combination with certain drugs, so always inform your doctor or pharmacist of any medications you are taking.

Serious side effects

Hives, severe swelling (angioedema), anaphylaxis, Stevens-Johnson syndrome, exfoliative skin diseases, acute pancreatitis, renal function deterioration (including acute renal failure), severe and disabling joint pain, blistering dermatitis, rhabdomyolysis, severe hypoglycemia, pneumonia, diabetic complications, metabolic acidosis, cardiac arrest

Mild side effects

• Pharyngitis
• upper respiratory tract infections
• headache
• diarrhea
• nausea
• constipation
• muscle pain
• limb pain
• back pain
• itching

Store this medication in a tightly sealed container to protect it from air and moisture. It is recommended to maintain a storage temperature between 1°C and 30°C at room temperature to help preserve the medication's effectiveness and safety.

Appearance

Pale orange, round, biconvex film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP X 3]