Danjijanujeong 100 Milligrams (Sitagliptin Hydrochloride Hydrate)

Adult dosage

This medication is administered as a single daily dose of 100 mg for monotherapy or combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment: - In cases of mild and moderate renal impairment (glomerular filtration rate eGFR 45 or greater and less than 90), no dose adjustment is needed. - For moderate renal impairment with a glomerular filtration rate of 30 or greater but less than 45, administer 50 mg once daily. - For severe renal impairment...

This medication may cause severe allergic reactions; if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after taking it, stop taking the medication immediately and seek medical attention. Additionally, serious inflammation of the pancreas, known as acute pancreatitis, may occur; therefore, if severe abdominal pain, vomiting, or nausea appears during use, consult a healthcare professional immediately. Patients with type 1 diabetes or diabetic ketoacidosis, as well as those who have had allergic reactions to this medication or its components, should not take it. Patients with impaired kidney function may have difficulties in excreting the drug, necessitating dose adjustment and regular kidney function tests. While taking this medication, there is a risk of hypoglycemia, especially when taken in conjunction with other hypoglycemic agents such as insulin or sulfonylureas; thus, blood sugar levels should be carefully monitored. Rare side effects such as severe joint pain or a blistering disease resembling dermatitis herpetiformis have been reported, and if these symptoms occur, consult a doctor immediately. The use of this medication is not recommended in pregnant or breastfeeding women, and safety and effectiveness have not been established for children or adolescents under 18 years of age. Elderly patients may experience decreased kidney function, so careful dose adjustments are needed, along with regular assessments of kidney function. In cases of overdose, general emergency measures should be followed, and if necessary, some of the drug can be removed through hemodialysis. This medication has minimal interactions with other drugs, but be sure to inform healthcare providers of any medication taken and receive appropriate monitoring.

Serious side effects

• Hives
• severe swelling (angioedema)
• anaphylaxis
• chest tightness
• difficulty breathing
• cold sweats
• pallor
• severe rash accompanied by high fever
• blisters
• skin peeling

Mild side effects

Pharyngitis, upper respiratory infection, headache, diarrhea, nausea, abdominal pain, constipation, vomiting, muscle pain, limb pain, back pain, pruritus, thrombocytopenia, severe joint pain, blistering disease resembling dermatitis herpetiformis, hypoglycemia, indigestion, dizziness, increased serum triglycerides, increased low-density lipoprotein, hyperglycemia, weight loss, hypertension, hypernatremia, erectile dysfunction

This medication should be stored in a tightly sealed container to prevent exposure to air or moisture. It is best stored at room temperature between 1°C and 30°C, avoiding extremely hot or cold environments.

Appearance

Light orange, round, biconvex, film-coated tablet

Package unit

30 tablets/box [10 tablets/PTPX3]