Dajibio New Jeong 50 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dosage

The standard dosage is 100 mg once daily for use as monotherapy or in combination therapy, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustments are necessary based on kidney function. - No dosage adjustments are required for patients with mild renal impairment (eGFR 60-90 mL/min/1.73 m2) and moderate renal impairment (eGFR 45-60 mL/min/1.73 m2).

This medication may rarely cause severe allergic reactions, so if symptoms such as skin rash, difficulty breathing, or swelling of the face or neck occur after administration, it should be discontinued immediately and medical advice should be sought. While taking this medication, there can be serious side effects such as acute pancreatitis, which involves inflammation of the pancreas, so if abdominal pain, vomiting, or severe abdominal discomfort occurs, notify medical staff immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, nor in cases of allergies to the drug or its ingredients. Patients with impaired renal function may require dosage adjustments; thus, those with kidney disease or issues regarding kidney function should consult with a physician to determine the appropriate dose. This medication may cause symptoms of hypoglycemia, particularly if taken with other blood-sugar-lowering agents such as insulin or sulfonylureas, necessitating careful monitoring of blood sugar levels. Severe joint pain or skin disorders such as blistering dermatosis similar to pemphigus may occur; thus, medical staff should be notified immediately if these symptoms arise. Pregnant or breastfeeding women are advised not to take this medication, and safety in pediatric patients under 18 years of age has not been established, so it is recommended not to use it. This medication may interact with other drugs; hence, it is essential to inform medical staff about other medications currently being taken and to consult for advice. In case of an overdose, standard treatment such as removal of the medication from the gastrointestinal tract is necessary, and some may be removed through dialysis, so appropriate actions should be taken following medical staff directions. The elderly may experience decreased kidney function, thus requiring regular assessment of renal function before and during treatment with this medication, and dosage adjustments may be necessary.

Serious side effects

Urticaria, severe swelling (angioedema), anaphylaxis, rash, exfoliative skin disorders (including Stevens-Johnson syndrome), acute pancreatitis, acute renal failure, severe and debilitating arthralgia, blistering dermatosis, jaundice, severe allergic reactions, severe skin adverse reactions, severe swelling or urination abnormalities

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• nausea
• abdominal pain
• constipation
• vomiting
• thrombocytopenia
• myalgia

This medication should be stored in a tightly sealed container to prevent air from entering, and it is best kept at room temperature between 1 to 30 degrees Celsius. This will maintain the medication's effectiveness and ensure safe usage.

Appearance

A pale yellow-pink, round, biconvex film-coated tablet

Package unit

30 tablets/box [10 tablets/PTPX3]