Janugliflozin Tablets 50 mg (Sitagliptin Hydrochloride Monohydrate)

Adult dose

This medication is administered as a single or combination therapy of 100 mg once daily, with a maximum daily dose of 100 mg. It can be taken regardless of meals. For patients with renal impairment, dosage adjustments are necessary based on renal function. 1. In mild renal impairment (eGFR 60-90 mL/min/1.73 m2), no dosage adjustment is necessary. 2. In moderate renal impairment (eGFR 45-60 mL/min/1.73 m2)

This drug may cause allergic reactions; if symptoms such as skin rash or difficulty breathing occur during use, discontinue immediately and consult a physician. This medication can cause serious inflammation of the pancreas known as pancreatitis; if symptoms such as abdominal pain, vomiting, or loss of appetite occur, inform medical staff immediately. This medication should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and it should not be administered to individuals with hypersensitivity to the drug or components. Patients with impaired kidney function may need dose adjustments for this medication, particularly those with low glomerular filtration rates or requiring dialysis should follow a doctor's instructions. There is a risk of hypoglycemia when taking this medication; if taken with insulin or sulfonylureas, it is important to monitor blood sugar levels frequently and adjust dosages as needed. If severe joint pain or skin blisters develop during use, stop taking the medication immediately and seek medical attention. Use during pregnancy or breastfeeding is not recommended, especially breastfeeding mothers should avoid taking this medication. Elderly individuals may experience decreased kidney function, so renal function should be assessed before taking this medication, and dosage adjustments may be necessary. In case of overdose, seek medical attention immediately for appropriate treatment, as some can be removed through hemodialysis; it is important to inform medical personnel.

Serious side effects

Urticaria, severe hypersensitivity reactions (anaphylaxis, angioedema, Stevens-Johnson syndrome, and other exfoliative skin diseases), acute pancreatitis (including hemorrhagic or necrotizing), severe allergic reactions, severe skin adverse reactions, liver abnormalities (elevated liver enzyme levels, suspected jaundice), acute renal failure, severe joint pain associated with disability, bullous pemphigoid, rhabdomyolysis, hypoglycemia (including severe), cardiac arrest, pneumonia, diabetic complications

Mild side effects

• Nasopharyngitis
• upper respiratory infection
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• vomiting
• myalgia
• limb pain

This medication should be stored in a tightly sealed container to prevent air ingress and kept at room temperature between 1 and 30 degrees Celsius. Proper storage maintains the drug's efficacy and safety.

Appearance

Pale orange, round, biconvex, film-coated tablet

Package unit

28 tablets/patty [14 tablets/patty * 2]