Esliptin Tablet 100 mg (Sitagliptin Hydrochloride Hydrate)

Adult dose

This medication is administered once daily at a dosage of 100 mg, whether alone or in combination, with a maximum daily dosage of 100 mg. It can be taken without regard to meals. For patients with renal impairment, dose adjustments are necessary based on renal function. - Mild renal impairment (eGFR 60-90): No dose adjustment required - Moderate renal impairment (eGFR 45-60): No dose adjustment required - Moderate renal impairment (eGFR 30-45): 1 dose of 50 mg daily

This medication can cause hypersensitivity reactions. If symptoms of allergy or severe skin conditions appear, discontinue use immediately and consult a physician. During use, symptoms of pancreatitis may occur; thus, if symptoms such as abdominal pain or vomiting appear, promptly inform a healthcare professional. It should not be administered to patients with type 1 diabetes or diabetic ketoacidosis. Patients with renal impairment should have their dose adjusted, and regular renal function tests are important. This medication can induce hypoglycemia, so when taken with insulin or sulfonylurea, careful monitoring of blood sugar levels is necessary. If severe joint pain or skin blistering symptoms occur, inform a doctor immediately, and discontinue the medication if necessary. Its use is not recommended during pregnancy; if breastfeeding, it is advisable to avoid taking this medication. Safety in children and adolescents has not been established, so it is preferable not to use it in individuals under 18 years of age. Elderly patients may have reduced renal function; therefore, dose adjustments and renal function tests are needed. In the event of overdose, immediately see a healthcare institution for appropriate treatment; some may be removed through hemodialysis. While taking this medication, symptoms of infection or gastrointestinal symptoms, headaches, dizziness, or other abnormal reactions may occur, so careful observation is required. There may be interactions with other medications, so inform the healthcare provider of all medications being taken.

Serious side effects

Urticaria, severe swelling (edema), anaphylaxis, angioedema, exfoliative skin diseases including Stevens-Johnson syndrome, acute pancreatitis, acute renal failure, severe and disabling joint pain, bullous pemphigoid, rhabdomyolysis, elevated liver enzymes, liver abnormalities (jaundice), severe hypoglycemia, pneumonia, diabetes complications, metabolic acidosis, falls, cardiac arrest, severe allergic reactions, severe skin adverse reactions, breathing difficulties, serious

Mild side effects

• Pharyngitis
• upper respiratory infection
• headache
• diarrhea
• nausea
• constipation
• myalgia
• limb pain
• back pain
• pruritus

This medication should be stored in a tightly sealed container to prevent air or moisture ingress. It is also advisable to store at room temperature between 1 to 30 degrees Celsius. Proper storage will help maintain the medication's efficacy for a longer period.

Appearance

Light orange, round, biconvex film-coated tablet

Package unit

30 tablets - 10 tablets/PTP[x3]