Janudam 25 mg (Sitagliptin Hydrochloride Dihydrate)

Adult dose

This medication is administered once daily at a dosage of 100 mg, with a maximum daily dose of 100 mg for either monotherapy or combination therapy. It can be taken regardless of meals. In patients with renal impairment, dosage adjustments are necessary according to renal function. - Mild renal impairment (estimated glomerular filtration rate [eGFR] 60-90 mL/min/1.73 m2): No dosage adjustment needed - Moderate renal impairment (estimated glomerular filtration rate [eGFR] 45-60 mL/min/

This medication may cause severe allergic reactions; if symptoms such as skin rash or difficulty breathing occur, discontinue use immediately and consult a doctor. Acute pancreatitis is a serious potential side effect, so if symptoms such as abdominal pain or vomiting arise, seek medical attention immediately. This drug should not be used in patients with type 1 diabetes or diabetic ketoacidosis, and it should also be avoided in cases of allergy to this drug or its components. For patients with impaired renal function, dosage adjustment is necessary, and regular kidney function monitoring is important. When used with other diabetes medications or insulin that may cause hypoglycemia, be cautious of hypoglycemic symptoms, and adjustment of doses of other medications may be necessary if needed. If severe joint pain or skin blistering occurs during treatment, notify a doctor immediately, as the medication may need to be discontinued. Pregnant or breastfeeding women should avoid using this medication, and its safety and efficacy have not been established in individuals under 18 years of age. Elderly patients may have diminished renal function, so care is necessary during administration, and regular renal function tests are recommended. In case of overdose, appropriate treatment should be provided according to symptoms, and some medications may be removed by dialysis. Finally, while this medication has relatively few drug interactions, follow a doctor’s instructions when used in conjunction with certain medications.

Serious side effects

• Urticaria
• angioedema
• anaphylaxis
• Stevens-Johnson syndrome
• exfoliative skin disease
• acute pancreatitis
• acute renal failure
• severe hypoglycemia
• severe arthralgia with complications
• blistering dermatitis

Mild side effects

• Upper respiratory infection
• nasopharyngitis
• headache
• diarrhea
• abdominal pain
• nausea
• constipation
• vomiting
• myalgia
• limb pain

This medication should be stored in a tightly sealed container to prevent air and moisture exposure, at room temperature between 1 to 30 degrees Celsius. Proper storage prolongs the drug’s effectiveness.

Appearance

Pink, round, biconvex film-coated tablet

Package unit

30 tablets/box (10 tablets/PTP X 3)