Angkuk Dutasteride Soft Capsule 0.5mg (Dutasteride)

Adult dose

The recommended dose of this medicine is 1 capsule (0.5mg) once daily. Because exposure to the capsule contents may cause irritation of the oropharyngeal mucosa, swallow the capsule whole without chewing or splitting it. This medicine may be taken with or without food. No dose adjustment is necessary in patients with renal impairment or elderly patients. The recommended dose of this medicine has not been established in patients with hepatic impairment because no data are available on its use in these patients.

This medication must not be handled or taken by women, especially those who are pregnant or may become pregnant, as it can be absorbed through the skin and potentially affect the development of the external genitalia of a male fetus. Children, especially those under 18 years, should not use this medication and should be cautious to avoid contact with it. If the capsule leaks and comes into contact with the skin, it must be washed immediately with soap and water. This medication is contraindicated in certain patients. For example, women and children under 18, and individuals who are allergic to this drug or similar medications should not use it. Adult men planning to conceive, patients with a high residual urine volume or significant decrease in urinary flow, patients with poor liver function, and patients taking strong CYP3A4 enzyme inhibitors should exercise special caution when using this drug. While taking this medication, sexual dysfunction side effects may occur, and erectile dysfunction, decreased libido, and ejaculation disorders have been reported. These symptoms may persist even after discontinuation of the medication, so consultation with a physician is advised. Long-term use may lead to breast-related side effects such as breast tenderness or breast enlargement, and the relationship with male breast cancer occurrence is still unclear. This drug may increase the risk of prostate cancer, so men taking it should regularly check their prostate health through prostate-specific antigen (PSA) testing and digital rectal exams. During and at least 6 months after taking this medication, blood donation should be avoided to prevent it being transmitted through transfusion to pregnant women. There is no specific antidote for overdose, so appropriate supportive treatment should be received if symptoms appear, and this medication has a long half-life, which means it can remain in the body for an extended period. This medication should be kept out of reach of children and stored in its original container to prevent misuse or degradation of quality. The potential for drug interactions exists, particularly for patients taking CYP3A4 inhibitors, and consultation with a physician or pharmacist is necessary before use. The likelihood of affecting driving or machine operation skills is low, but caution is needed if side effects occur. This drug may affect male fertility, and long-term use may result in decreased sperm count or semen volume, so this should also be considered.

• erectile dysfunction
• decreased libido
• ejaculation disorder
• gynecomastia
• headache
• gastrointestinal discomfort and pain
• sexual dysfunction
• breast disorders
• dizziness
• rash

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. Additionally, it is important to store it at a cool temperature below 30 degrees Celsius to maintain its efficacy and safety.

Appearance

A transparent yellowish oval soft capsule containing a colorless transparent liquid.

Package unit

30 capsules/PTP [(15 capsules/PTPX2, 10 capsules/PTPX3)]