Olpro Tablet 20/20 mg

Adult dose

The recommended starting dose of Olmesartan Medoxomil is 10 mg once daily, administered regardless of meals. If blood pressure is not adequately controlled, it may be increased to 20 mg once daily, with a maximum dose of 40 mg per day. Rosuvastatin's starting dose is 5 mg once daily, with administration at any time of the day regardless of meals. The maintenance dose is 10 mg once daily, and if necessary, may be increased to a maximum of 20 mg per day.

Child dose

Safety and efficacy in pediatric patients under 18 years have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy; therefore, if pregnancy is confirmed, it must be discontinued immediately. This medication should not be used in women who are allergic to any component, pregnant or breastfeeding, patients with severely impaired renal function, or those with severe liver disease. Patients with decreased blood volume or those taking significant doses of diuretics should be closely monitored for hypotension upon initial dosing. Patients with impaired renal function or kidney transplant recipients, as well as those with renovascular hypertension, should have their renal function and serum electrolyte levels regularly checked during treatment. Due to the risk of hyperkalemia, potassium levels in the blood should be checked periodically, and caution is advised in patients with cardiac or aortic abnormalities. Muscle-related adverse reactions may occur; if symptoms of myalgia or muscle weakness arise, the physician should be notified immediately. Patients with a history of excessive alcohol consumption or liver disease should be monitored closely and undergo regular liver function tests while using this medication. Specifically, the Rosuvastatin component of this medication may cause serious side effects such as liver damage, myopathy, and rarely, rhabdomyolysis. This medication may interact with other drugs, so if taking other medications, patients must inform their physician or pharmacist. Women who are pregnant or planning to become pregnant should use appropriate contraception, and breastfeeding should be ceased if using this medication. Elderly patients may have increased concentration of this medication in their bodies, necessitating dosage adjustments and careful monitoring. Overdose may lead to symptoms such as hypotension and palpitations; as there are no specific antidotes, symptomatic treatment should be administered. This medication has not been established for safety and efficacy in children and should not be used by them. Store this medication out of reach of children, and do not transfer it to other containers.

Serious side effects

Hives, severe swelling (edema), angioedema, facial edema, chest tightness, difficulty breathing, anaphylaxis, severe allergic reactions, severe skin reactions, hives, angioedema, alopecia, pruritus, severe skin reactions (Stevens-Johnson syndrome, DRESS), liver abnormalities (jaundice, hepatitis, fatal or non-fatal liver failure), acute renal failure, rhabdomyolysis, serious neurological symptoms (including seizures)

Mild side effects

• Headache
• dizziness
• sensory loss
• drowsiness
• gastroesophageal reflux
• constipation
• dental caries
• dyspepsia
• gastric ulcer
• gastritis

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. It is advisable to maintain the storage temperature between 1 and 30 degrees Celsius.

Appearance

White or yellowish round film-coated tablets

Package unit

30 tablets/box [(10 tablets/Alu-Alu) x 3]