Esmed Tablet (Esamlodipine Besylate Hydrate 2.5)

Adult dose

The recommended oral dosage is 2.5 mg of esamlodipine once daily, which may be increased to a maximum of 5 mg daily based on the patient’s response. Adjust according to symptoms.

It is crucial that this medication is not used in certain patients. For instance, individuals who have had allergies or hypersensitivity reactions to this medication or its components should not take it. It should also not be administered to pregnant women, women who may become pregnant, or women who are breastfeeding. Patients in shock with severely impaired heart conditions or significant valvular heart disease should also avoid this medication. Furthermore, patients with unstable angina, recent myocardial infarction, severe liver dysfunction, or hypotension should refrain from using this medication. Patients with severely impaired kidney function, the elderly, patients with acute heart failure, patients in hypertensive crisis, and patients with moderate liver dysfunction should use this medication with caution. Patients should be aware of various side effects that may occur rarely when taking this medication. The most common side effects include flushing and heating, fatigue, swelling of the legs or ankles, palpitations, dizziness, headache, indigestion, and drowsiness. Additionally, rare side effects such as dry mouth, increased sweating, decreased blood pressure, insomnia, skin rash, and liver function abnormalities may occur, so if any unusual symptoms arise, they should consult a doctor immediately. Sudden discontinuation of this medication may worsen symptoms, so it should be gradually reduced under a doctor’s guidance. Patients with heart failure or poor liver function should take special care, and blood pressure should be regularly monitored to ensure it does not drop too low. It is advisable to take this medication with plenty of water, as low blood pressure may result in dizziness or fatigue. Extra caution is required when driving or engaging in hazardous tasks. Moreover, this medication may interact with various other medications, so it is essential to inform your doctor or pharmacist of any current medications being taken. Particularly, taking this medication with grapefruit juice may intensify its effects and is therefore not recommended. Women who are pregnant or breastfeeding should not take this medication, and if breastfeeding, it is safer to discontinue breastfeeding. Use is only recommended for children aged 6 years and older, as safety and efficacy have not been established for children under 6 years of age. For the elderly, this medication may remain in the body for longer periods; thus, it is advisable to start with a low dose and gradually increase it. In cases of overdose, severe hypotension, cardiac abnormalities, or shock may occur, necessitating immediate hospital treatment; blood dialysis will not be effective. Lastly, this medication should be kept out of reach of children and should not be transferred to other containers for safety reasons.

Serious side effects

Urticaria, severe swelling (edema), angioedema, toxic epidermal necrolysis, Stevens-Johnson syndrome, pruritus, jaundice, symptoms of acute liver dysfunction (weakness, anorexia, persistent nausea), paralysis, myocardial infarction, arrhythmia, chest pain, severe edema associated with elevated blood pressure, atrioventricular block, loss of consciousness, coma, shock, difficulty breathing, dyspnea

Mild side effects

• Flushing
• fatigue
• edema
• palpitations
• dizziness
• headache
• migraine
• weakness
• abdominal pain
• nausea

This medication may be sensitive to air or moisture, so it must be stored in a tightly sealed container. The storage temperature should be maintained between 1 and 30 degrees Celsius at room temperature. Storing it this way will help maintain the medication’s efficacy and safety over time.

Appearance

Light yellow heart-shaped tablet with a score line

Package unit

30 tablets/bottle, 300 tablets/bottle