Pioglitazone Tablets 30 mg (Pioglitazone Hydrochloride)

Adult dose

This medication is taken orally once a day regardless of meals. The therapy starts with 15 mg once a day and can be increased to 30 mg once a day if not sufficiently effective. In combination therapy, it is administered with sulfonylureas, metformin, or insulin at a dose of 15 mg once a day, and the maximum recommended dose should not exceed 30 mg once a day.

Child dose

Experience with patients under 18 years is lacking, hence administration is not recommended.

This medication is used in the treatment of type 2 diabetes and works to improve insulin resistance. When taking this medication, there is a risk of heart failure occurring or worsening, so weight changes, breathing difficulties, swelling, and other symptoms should be closely monitored. Patients with heart failure or a history of heart failure should not use this medication, and if symptoms of heart failure appear, a doctor should be consulted immediately. This medication can cause fluid retention, which may lead to swelling; therefore, if swelling symptoms arise, medical staff should be informed. Additionally, this medication is not administered to patients with a history of bladder cancer or currently active bladder cancer. It is also safe not to use this medication in cases of poor liver function or severe renal impairment. Women who are pregnant or may become pregnant should not use this medication, and women who are premenopausal should exercise appropriate contraception during treatment as there may be an increased chance of becoming pregnant while taking this medication. There is a risk of hypoglycemia, so when combined with insulin or other hypoglycemic agents, one should be cautious for symptoms of hypoglycemia, and dosage adjustment of other medications may be necessary. Routine liver function tests should be conducted while using this medication, and if symptoms of liver dysfunction arise, medical staff should be informed immediately. If sudden weight gain, swelling, or shortness of breath occurs during treatment, consult a physician immediately. Elderly patients or those with renal function impairment require even more careful monitoring during treatment with this medication. In the case of overdose, even in the absence of specific symptoms, contact a medical institution immediately to receive appropriate treatment. This medication may interact with certain drugs, so be sure to inform medical staff of any other medications being taken. Finally, this medication has not established safety or efficacy in children, so it is not to be used in this population.

Serious side effects

Congestive heart failure, worsening heart failure, symptoms of heart failure (shortness of breath, swelling), severe rash with high fever, blistering, peeling of skin, pain in the oral/ocular mucosa, difficulty in breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of skin or eyes (jaundice), extreme drowsiness, sudden and very severe headache, thunderclap headache, seizures, confusion, visual disturbances, paralysis, markedly reduced urine output

Mild side effects

• Headache
• upper respiratory tract infection
• sinusitis
• myalgia
• pharyngitis
• abdominal bloating
• weight gain
• hypoglycemia
• urinary tract infection
• low back pain

This medication should be stored in a container that does not allow light and air to enter, and should be kept away from humid places. The optimal storage temperature is 25 degrees Celsius, and it can be safely stored between 15 and 30 degrees Celsius.

Appearance

White round tablet

Package unit

30 tablets/bottle, 100 tablets/bottle