Ildong Esomeprazole Magnesium Trihydrate 20 mg

Adult dosage

This medication must be swallowed with liquid, and should not be chewed or crushed. 1) Gastroesophageal reflux disease (GERD) - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - If esophagitis remains untreated or symptoms persist, an additional 4 weeks of treatment is required - Long-term maintenance therapy to prevent recurrence: 20 mg once daily - Treatment of gastroesophageal reflux disease symptoms without esophagitis: 1

Children's dosage

Adolescents over 12 years - Treatment of erosive reflux esophagitis: 40 mg once daily for 4 weeks - Treatment of gastroesophageal reflux disease symptoms without esophagitis: 20 mg once daily - Symptoms

This medication should not be administered to certain patients. It must not be taken by those with hypersensitivity to this drug or its components, or to benzimidazole derivatives. Patients allergic to certain antibiotics such as amoxicillin or clarithromycin during Helicobacter pylori eradication therapy should also refrain from using this drug. It is advisable for individuals with a history of myocardial infarction or those who are breastfeeding to avoid this medication. This drug contains the dye Yellow No. 5; therefore, those with allergies or hypersensitivity to this component should use it cautiously. While taking this medication, there may be various adverse reactions. Blood-related issues such as leukopenia or thrombocytopenia may occur rarely, and severe allergic reactions may also happen infrequently. Electrolyte disturbances like hypomagnesemia have been reported rarely, and this may accompany calcium or potassium deficiencies. Mental symptoms such as insomnia, anxiety, depression, and hallucinations may occur, and headaches or dizziness may frequently be experienced. Gastrointestinal issues including abdominal pain, constipation, diarrhea, nausea, and vomiting can occur commonly, although severe problems such as pancreatitis or gastric mucosal inflammation may rarely arise. Severe skin reactions such as rashes, itching, hair loss, and in severe cases, Stevens-Johnson syndrome have also been reported. Muscle pain or joint pain may occur, and renal issues such as nephritis can very rarely be encountered. This medication may mask symptoms of malignant tumors when used over a long duration, so if there are symptoms like weight loss, recurrent vomiting, blood vomiting, or black stools, consulting a doctor is essential. Regular examinations are necessary for prolonged use over one year, and immediate medical attention should be sought if there are changes in symptoms. This drug can lower gastric acidity, increasing the risk of bacterial infections; therefore, if diarrhea persists for a long time, the healthcare provider should be informed. There may be an increased risk of fractures with prolonged high-dose use, so periodic monitoring is required for those at risk of osteoporosis. Additionally, prolonged use beyond three months may lead to hypomagnesemia, necessitating regular checks of magnesium levels. This drug has numerous interactions with other medications, so caution is required, especially when used with anticoagulants, antibiotics, antiviral drugs, and anticonvulsants. Patients should always inform their doctor or pharmacist about any currently taken medications, as interactions with other drugs can cause adverse effects. Data on the safety of this medication during pregnancy are limited, so pregnant women should take it cautiously under a doctor’s guidance, and it is preferable to avoid it during breastfeeding. There is no specific antidote for overdose, so appropriate management should be provided based on symptoms, and this drug binds strongly to proteins in the blood, making it unrecoverable through dialysis. Lastly, this drug should be kept out of the reach of children, and transferring it to another container can lead to quality degradation or accidents, so caution is advised.

Serious side effects

• Urticaria, severe swelling (edema), angioedema, chest tightness
• Difficulty breathing, asthmatic attacks, respiratory distress, bronchospasm
• Cold sweat, pallor
• Fever with severe rash, blisters, mucosal pain in the mouth/eyes
• Jaundice, liver failure, encephalopathy in patients with liver disease
• Sudden and severe headache, seizures, confusion, visual disturbances, paralysis
• Significant reduction in urine output, severe body swelling, increased blood pressure

Mild side effects

• Blood and lymphatic system: leukopenia, thrombocytopenia, agranulocytosis, pancytopenia
• Immune system: fever, angioedema, allergic reactions
• Metabolism/Nutrition: peripheral edema, hyponatremia, hypomagnesemia
• Psychiatric: insomnia, anxiety, confusion, depression, aggression, hallucinations
• Nervous system: headache, dizziness, sensory disturbances, drowsiness, taste alterations
• Vision: blurred vision
• Auditory and labyrinthine: dizziness
• Respiratory: bronchospasm
• Gastrointestinal: pancreatitis, abdominal pain

This medication should be stored in a tightly sealed container to protect it from air and moisture, and it should be kept at a temperature between 1 and 30 degrees Celsius (room temperature). Therefore, always make sure to close the lid well when storing the medication and avoid extremely hot or cold places.

Appearance

Pale pink oblong film-coated tablets

Package unit

28 tablets/box [14 tablets/Alu-Alu*2]