Medication info
Lafutinin Tablet (Lafutidine)

Lafutinin Tablet (Lafutidine)

Prescription medicationTabletOral
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Geonil Biopharm Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202003718 · Approved 2020.05.21 · Insurance code 073000860

Summary

Main use
Treatment of gastrointestinal disorders (such as ulcers, gastritis, and reflux esophagitis); preanesthetic medication; adjunctive treatment for Helicobacter pylori eradication
Who takes it
Adults
Adult dose
1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. Clinical studies with treatment for up to 8 weeks showed healing in most patients within 8 weeks, although the healing period may occasionally vary by patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. Clinical studies with treatment for up to 6 weeks showed healing in most patients within 6 weeks, although the healing period may occasionally vary by patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. Clinical studies with treatment for up to 2 weeks showed healing in most patients within 2 weeks, although the healing period may occasionally vary by patient. 4. Combination antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per administration, given twice orally (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Ingredients

Manufacturer
Geonil Biopharm Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (such as ulcers, gastritis, and reflux esophagitis); preanesthetic medication; adjunctive treatment for Helicobacter pylori eradication

  • Gastric ulcer
  • duodenal ulcer
  • gastric mucosal lesions from acute gastritis
  • chronic gastritis
  • peptic ulcer
  • gastroesophageal reflux disease
View approved original text

This medication is used to treat gastric ulcers and duodenal ulcers. It also helps improve gastric mucosal damage due to acute and chronic gastritis. For patients with peptic ulcers infected with Helicobacter pylori, it is taken in conjunction with antibiotics to enhance the treatment effect. It is also used as a preoperative medication before anesthesia, and is effective in treating gastroesophageal reflux disease. It effectively acts on various gastrointestinal diseases, improving symptoms in patients.

How to take

Adult dose

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. Clinical studies with treatment for up to 8 weeks showed healing in most patients within 8 weeks, although the healing period may occasionally vary by patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and before bedtime. Clinical studies with treatment for up to 6 weeks showed healing in most patients within 6 weeks, although the healing period may occasionally vary by patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily before bedtime. Clinical studies with treatment for up to 2 weeks showed healing in most patients within 2 weeks, although the healing period may occasionally vary by patient. 4. Combination antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per administration, given twice orally (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine orally twice daily.

Precautions

This medication should not be used by patients who are allergic to any of its ingredients. It also contains lactose, so patients with a genetic condition affecting lactose breakdown should not take this medication. Those allergic to soybean oil, soy, or peanuts should also avoid this medication. Patients with a history of drug allergies, or those with liver or kidney dysfunction, patients undergoing dialysis, and elderly individuals should be cautious when using this medication. Patients with abnormalities in fat metabolism or those taking lipid-lowering medications should also be administered with caution. This medication may rarely cause severe allergic reactions, liver dysfunction, or blood cell reductions, so if any symptoms occur, the medication should be discontinued immediately, and medical consultation should be sought. Additionally, various side effects such as gastrointestinal symptoms, headache, dizziness, and rash have been reported, so careful monitoring is necessary. If symptoms suggesting malignancy or suspected gastric cancer are present, testing should be completed before taking this medication, following the physician's instructions. During treatment, regular blood tests and liver and kidney function tests should be performed to check for any abnormalities. Particularly, patients at risk of fat overload should check their blood lipid levels and adjust the dosage if necessary. Elderly patients may have reduced physical function, so special care should be taken regarding the dosage and administration interval. Patients undergoing dialysis may have elevated blood drug concentrations, so treatment should begin at a low dose and be administered with caution. Pregnant or breastfeeding women should only use this medication if necessary, as it may affect the fetus or newborn, based on the physician's judgment. Safety in children has not been established, so it should be administered cautiously to pediatric patients. This medication should be kept out of reach of children and stored in its original container to prevent misuse or quality degradation.

Side effects

  • Shock
  • anaphylactic symptoms
  • pallor
  • hypotension
  • generalized rash
  • dyspnea
  • hepatic dysfunction
  • jaundice
  • agranulocytosis
  • pharyngitis
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  • generalized fatigue
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • seizures
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Lyell syndrome
  • rhabdomyolysis
  • atrioventricular block
  • heart failure
  • constipation
  • diarrhea
  • hard stool
  • nausea
  • vomiting
  • abdominal bloating
  • loss of appetite
  • headache
  • insomnia
  • drowsiness
  • reversible confusion
  • hallucinations
  • consciousness disturbance
  • dizziness
  • chills
  • warmth sensation
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • elevated TTT
  • abnormal urinary protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • delayed physiology
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • fatigue
  • glossitis
  • headache
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • distension
  • rhinitis
  • upper respiratory infection
  • bronchopneumonia
  • tinea
  • cough
  • oropharyngeal pain
  • oropharyngeal discomfort
  • wet cough
  • fatigue
  • chest pain
  • limb pain
  • arthralgia
  • cervical pain
  • itching
  • acne
  • contusion
  • insomnia
  • non-alcoholic fatty liver disease

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent exposure to air or moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.