Celocapsule 100mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted according to the patient and may be taken with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) Take celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. 2. Rheumatoid arthritis Take celecoxib 100 mg or 200 mg twice daily. 3. Ankylosing spondylitis (AS) Administer celecoxib 200 mg once daily, or 100 mg twice daily in divided doses. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment at 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea The recommended initial dose is celecoxib 400 mg, with an additional 200 mg on the first day of treatment if needed. From the second day onward, the recommended dose, if needed, is 200 mg twice daily. ○ Patients with hepatic impairment In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication should be consulted with a doctor or pharmacist for those who regularly consume more than three glasses of alcohol daily. Taking this drug with alcohol can increase the risk of gastrointestinal bleeding. It is important to use the lowest effective dose for the shortest duration possible, as this medication may increase the risk of thrombotic events, myocardial infarction, and stroke. Even without a history of cardiovascular disease, careful monitoring for symptoms such as chest pain, shortness of breath, weakness, and slurred speech is necessary, and immediate action should be taken if any of these arise. Gastrointestinal complications such as perforation, ulcers, and bleeding may occur; thus, inform healthcare professionals immediately if any symptoms like epigastric pain, indigestion, black stools, or hematemesis arise during treatment. Caution is especially needed for elderly patients due to the higher risk of gastrointestinal adverse reactions. This medication is contraindicated for individuals with certain allergic reactions, severe liver or kidney impairments, active peptic ulcers or gastrointestinal bleeding, heart failure, pregnant or nursing women, and those with specific cardiovascular diseases. Patients with liver or kidney issues, asthma, hypertension, edema, or those undergoing diuretic therapy should use this drug cautiously and regularly check their condition according to their doctor's instructions. Regular monitoring of liver and kidney functions, blood tests, etc., should be performed during treatment, and the medication should be stopped immediately at any signs of abnormalities. This medication may cause drowsiness or dizziness; hence, driving or operating machinery should be avoided after taking it. Additionally, this medication can interact with other drugs, so inform healthcare professionals about any concurrent medications, especially blood pressure medications, diuretics, anticoagulants, antidepressants, and antibiotics. Women who are pregnant or planning to become pregnant should not take this medication, and if pregnancy is confirmed during use, it should be stopped immediately. Nursing women should also discontinue breastfeeding or consult a doctor if they take this medication. Safety in children and adolescents has not been established, thus it is advisable not to use in individuals under 18 years old. Elderly patients may have diminished renal, hepatic, and cardiac functions, necessitating more careful observation during administration. Finally, this medication should be stored out of reach of children, and it is advisable not to transfer it to another container.

Gastrointestinal bleeding, cardiovascular thrombotic events, myocardial infarction, stroke, upper and lower gastrointestinal perforation, ulcers, bleeding, bronchitis, sinusitis, upper respiratory tract infections, urinary tract infections, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusional state, dizziness, muscular hypertonicity, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, urticaria, angioedema, alopecia, vesicular dermatitis, peripheral edema, facial edema, influenza-like illness, damage, taste dysfunction, albuminuria, cystitis, hematuria, dysuria, increased urinary frequency, nephrolithiasis, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, ocular hemorrhage, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine occult blood, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, hallucinations, cerebral hemorrhage, aseptic meningitis, loss of taste, loss of smell, vasculitis, pulmonary embolism, interstitial pneumonia, gastrointestinal bleeding, hepatitis, liver failure, fulminant hepatitis, liver necrosis, bile stasis, biliary stasis hepatitis, jaundice, photosensitivity reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, drug rash with eosinophilia and systemic symptoms, acute generalized exanthematous pustulosis, exfoliative dermatitis, generalized blistering fixed drug eruption, fixed drug eruption, menstrual disorders, chest pain, dyspepsia, abdominal pain, nausea, peripheral edema, rash, diarrhea, insomnia, headache, dizziness, constipation, gastric ulcer, urticaria, anemia, thirst, ulcerative stomatitis, gastritis, allergy, low back pain, chest pain, hyperlipidemia, diabetes, weight gain, fractures, arthralgia, positive RA factor, shingles, pneumonia, dyspnea, elevated ALT, hearing loss, weakness, chest pain, fluid retention, systemic edema, facial swelling, fatigue, malaise, fever, facial flushing, influenza syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, headache, dizziness, leg cramps, tension increase, sensory depression, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, insomnia, anorexia, anxiety, increased appetite, depression, neuroexcitability, drowsiness, fatal intracranial hemorrhage, confusion, hallucinations, seizure exacerbation, upper respiratory tract infection, sinusitis, pharyngitis, rhinitis, bronchitis, bronchospasm, exacerbation of bronchospasm, cough, dyspnea, laryngitis, pneumonia, nosebleed, voice disorder, vesicular dermatitis, petechial hemorrhage, rash, alopecia, dermatitis, nail disease, photosensitive reaction, pruritus, erythematous rash, papular rash, skin disease, dry skin, increased sweating, urticaria, erythema multiforme, exfoliative dermatitis, mucous membrane syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechial hemorrhage, dandruff, drug rash with eosinophilia and systemic symptoms, vasculitis, pulmonary embolism, interstitial pneumonia, acute renal failure, hyponatremia, tubulointerstitial nephritis, nephrotic syndrome, micro-patch glomerulonephritis, female infertility

This medication should be stored in a tightly closed container to prevent air and moisture from entering, and it should be kept at room temperature between 15 to 30 degrees Celsius. Proper storage helps maintain the drug's effectiveness and prevents deterioration.

Appearance

A white capsule filled with a white to pale yellow powder, featuring a blue stripe on the upper and lower parts.

Package unit

100 capsules/bottle, 30 capsules/bottle