Opalo Tablets (Limaprost Aldex)

Adult dosage

1. For improvement of ischemic symptoms such as ulcers, pain, and coldness due to thromboangiitis obliterans (Buerger's disease), the usual adult dose is 2 tablets orally 3 times daily. 2. For improvement of subjective symptoms (lower-limb pain and numbness) and walking ability due to acquired lumbar spinal canal stenosis (in patients with normal SLR test results and bilateral intermittent claudication), the usual adult dose is 1 tablet orally 3 times daily. Adjust the dose as appropriate according to age and symptoms.

This medication should not be used in women who are pregnant or may become pregnant. This medication contains lactose, so it should not be administered to patients with a hereditary condition that impairs lactose digestion. Patients at risk of bleeding or those taking antiplatelets, thrombolytics, or anticoagulants should use this medication with caution. During the use of this medication, allergic reactions such as rashes or itching may occur, so if such symptoms appear, immediately discontinue use. Bleeding may occur rarely, so if bleeding symptoms appear, the medication should be stopped immediately, and medical personnel should be consulted. Gastrointestinal side effects may include diarrhea, nausea, abdominal discomfort, abdominal pain, decreased appetite, heartburn, vomiting, and abdominal bloating. Liver function abnormalities may occur, and liver function tests may be necessary. Cardiovascular symptoms such as palpitations, peripheral cyanosis, and hypotension may appear, so caution is needed. Symptoms such as headaches, facial flushing, dizziness, warmth, generalized fatigue, swelling, gland swelling, tremors, hirsutism, and anemia have also been reported. Patients with lumbar spinal stenosis should observe changes in symptoms to determine whether to continue using the medication. The efficacy of this medication has not been definitively proven in cases of severe spinal stenosis requiring surgery. Safety during pregnancy has not been established, and women who are pregnant or may become pregnant should not take this medication. Animal studies have reported uterine contraction effects, which may pose risks during pregnancy. Safety for children has not been confirmed, so it is best not to use it in pediatric patients. Elderly individuals may have decreased physical function; therefore, dosage may need to be adjusted, and caution should be taken during use. This medication has been shown to be bioequivalent to other products with the same ingredients.

• Rash
• itching
• bleeding
• diarrhea
• nausea
• abdominal discomfort
• abdominal pain
• loss of appetite
• heartburn
• vomiting

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. Additionally, the medication should be kept in a cool place, maintaining a temperature between 1 and 30 degrees Celsius.

Appearance

White round tablet

Package unit

84 tablets/box [21 tablets/Alu-Alu × 4]