Medication info
Lafuwon Tablet 10 mg (Lafutidine)

Lafuwon Tablet 10 mg (Lafutidine)

Prescription medicationTablet
Ingredient · strength
Lafutidine›10mg / 1 tablet
Manufacturer / importer
Hana Pharmaceutical Co., Ltd.
Appearance
White round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202003598 · Approved 2020.05.18 · Insurance code 657807360

Summary

Main use
Treatment of gastrointestinal disorders (ulcers, gastritis, gastroesophageal reflux disease, etc.); use in combination for eradication therapy; pre-anesthetic medication
Who uses it
Adults
Adult dosage
1. Short-term treatment of gastric ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was administered for up to 8 weeks, most ulcers healed within 8 weeks, although healing time may occasionally vary by patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was administered for up to 6 weeks, most ulcers healed within 6 weeks, although healing time may occasionally vary by patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10 mg of lafutidine orally once daily before bedtime. In clinical trials in which treatment was administered for up to 2 weeks, most lesions healed within 2 weeks, although healing time may occasionally vary by patient. 4. Combination antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication before anesthesia: The usual dose is 10 mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10 mg of lafutidine per dose orally twice daily.

Ingredients

Manufacturer
Hana Pharmaceutical Co., Ltd.

Efficacy & effects

Treatment of gastrointestinal disorders (ulcers, gastritis, gastroesophageal reflux disease, etc.); use in combination for eradication therapy; pre-anesthetic medication

  • Gastric ulcer
  • duodenal ulcer
  • gastric mucosal lesions due to acute gastritis
  • chronic gastritis
  • peptic ulcer
  • gastroesophageal reflux disease
View approved original text

This medication is used for the treatment of peptic ulcers, including gastric ulcers and duodenal ulcers. It also helps improve gastric mucosal damage caused by acute and chronic gastritis. For patients with peptic ulcers associated with Helicobacter pylori infection, it is effectively treated in combination with antibiotics. It is also used as premedication before surgery or procedures and is good for the treatment of gastroesophageal reflux disease. Overall, it is used to effectively treat gastrointestinal-related diseases and improve symptoms.

Dosage and Administration

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was administered for up to 8 weeks, most ulcers healed within 8 weeks, although healing time may occasionally vary by patient. 2. Short-term treatment of duodenal ulcers: The usual dose is 10 mg of lafutidine orally twice daily, in the morning and before bedtime. In clinical trials in which treatment was administered for up to 6 weeks, most ulcers healed within 6 weeks, although healing time may occasionally vary by patient. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10 mg of lafutidine orally once daily before bedtime. In clinical trials in which treatment was administered for up to 2 weeks, most lesions healed within 2 weeks, although healing time may occasionally vary by patient. 4. Combination antibiotic therapy in patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication before anesthesia: The usual dose is 10 mg of lafutidine per dose, administered orally twice (before bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10 mg of lafutidine per dose orally twice daily.

Precautions

This medication should not be used in patients who are allergic to its ingredients. Additionally, since this drug contains lactose, patients with genetic issues such as galactose intolerance, Lapp lactase deficiency, and glucose-galactose malabsorption should avoid taking it. Patients with a history of hypersensitivity to the drug or those with liver or kidney function issues, patients on dialysis, and elderly individuals should use this medication with caution. During the use of this drug, allergic reactions may lead to symptoms such as shock or anaphylaxis; if symptoms such as facial paleness, low blood pressure, generalized redness, or difficulty breathing occur, discontinue use immediately and consult medical personnel. Liver function impairment or jaundice may occur, so regular liver function tests should be conducted, and if abnormalities are found, the medication should be discontinued. There may be a decrease in the number of white blood cells or platelets; if symptoms such as sore throat, weakness, or fever appear, consult a doctor immediately. Additionally, serious side effects such as skin rashes, convulsions, and irregular heartbeats have been reported, so any unusual symptoms should be reported to medical personnel immediately. Common side effects reported in clinical trials include constipation, diarrhea, nausea, headache, drowsiness, dizziness, and facial flushing. If these symptoms persist or worsen, consult a professional. This drug may obscure symptoms of malignant tumors, so patients with gastric ulcers or suspected cases should undergo regular examinations to check for malignancy. Elderly patients may experience decreased bodily functions, so dosage and administration intervals should be adjusted, and the condition should be monitored carefully. Patients on dialysis may have increased plasma drug concentrations, so start at a low dose and administer carefully. Pregnant women or those who may become pregnant should take this medication only if deemed necessary by a doctor, and breastfeeding women should avoid it as it may be excreted in breast milk. Safety in pediatric patients has not been established, so use in children is not recommended. Finally, this medication should be stored out of reach of children and kept in its original container to prevent misuse or deterioration of quality.

Side effects

  • Shock
  • symptoms of anaphylaxis
  • facial pallor
  • hypotension
  • generalized rash
  • dyspnea
  • liver function impairment
  • jaundice
  • agranulocytosis
  • pharyngitis
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  • generalized malaise
  • fever
  • thrombocytopenia
  • pancytopenia
  • aplastic anemia
  • seizures
  • interstitial nephritis
  • Stevens-Johnson syndrome
  • Lyell's syndrome
  • rhabdomyolysis
  • heart block
  • heart failure
  • constipation
  • diarrhea
  • hard stool
  • nausea
  • vomiting
  • abdominal distension
  • loss of appetite
  • headache
  • insomnia
  • drowsiness
  • reversible confusional state
  • hallucinations
  • altered consciousness
  • dizziness
  • chills
  • burning sensation
  • facial flushing
  • leukocytosis
  • eosinophilia
  • leukopenia
  • erythrocytopenia
  • decreased hematocrit
  • elevated ALT
  • elevated AST
  • elevated Al-P
  • elevated γ-GTP
  • elevated T-Bil
  • elevated LDH
  • elevated TTT
  • abnormal urine protein
  • elevated BUN
  • elevated serum uric acid
  • elevated Cl
  • delayed growth
  • elevated Na
  • decreased K
  • gynecomastia
  • edema
  • malaise
  • glossitis
  • headache
  • chest pain
  • subdural hematoma
  • urticaria
  • skin rash
  • abdominal pain
  • dyspepsia
  • enteritis
  • gastric ulcer
  • erosive gastritis
  • duodenitis
  • bloating
  • nasopharyngitis
  • upper respiratory infection
  • bronchopneumonia
  • tinea
  • carotid artery stenosis
  • cough
  • oropharyngeal pain
  • oropharyngeal discomfort
  • wet cough
  • fatigue
  • chest pain
  • limb pain
  • arthralgia
  • cervical pain
  • pruritus
  • acne
  • contusion
  • insomnia
  • non-alcoholic fatty liver disease

Not everyone experiences these, and they can vary from person to person.

Storage

This drug may be sensitive to air or moisture, so it must be stored in a tightly sealed container. It is advisable to keep the storage temperature between 1 degree and 30 degrees Celsius at room temperature to ensure the drug's effectiveness.

Appearance and packaging

Appearance

White round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.