Medication info
Rasirect 1.0 mg (Rasagiline Mesylate)

Rasirect 1.0 mg (Rasagiline Mesylate)

Prescription medicationTabletOral
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
Anguk New Pharm Co., Ltd.
Appearance
White or almost white, flat round tablet with beveled edges
Packaging
30 tablets/bottle
Approval status
Active

MFDS item code 202003581 · Approved 2020.05.18

Summary

Main use
Treatment of idiopathic Parkinson’s disease
Who takes it
Adults
Adult dose
This drug is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended starting dose in patients taking levodopa is 0.5mg once daily. If well tolerated but the clinical response is inadequate, the dose may be increased to 1mg once daily. This drug may be taken with or without food.

Ingredients

Manufacturer
Anguk New Pharm Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson’s disease

  • Idiopathic Parkinson's disease
  • motor fluctuation symptoms
View approved original text

This medication is used as monotherapy or as an adjunct to dopamine agonists in the early stages of idiopathic Parkinson's disease. Additionally, it is used as an adjunctive therapy for patients experiencing motor fluctuations after taking levodopa during treatment, helping to alleviate symptoms. It is useful in improving the main symptoms of Parkinson's disease.

How to take

Adult dose

This drug is administered orally to adults once daily as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy with a dopamine agonist: Administer 1mg orally once daily. 2) Adjunctive therapy with levodopa: The recommended starting dose in patients taking levodopa is 0.5mg once daily. If well tolerated but the clinical response is inadequate, the dose may be increased to 1mg once daily. This drug may be taken with or without food.

Precautions

This medication should not be used by patients who are allergic to the active ingredient or any other ingredients. Patients currently taking or who have recently discontinued other MAO inhibitors or certain natural medicines should not use this medication. Patients taking certain medications such as pethidine, tramadol, or dextromethorphan should not use this medication together. This medication is not administered to patients with moderate to severe liver impairment. This medication can cause various side effects such as headaches, depression, hallucinations, dizziness, skin rashes, and myalgia. Particularly, patients with Parkinson's disease need to be cautious due to the possibility of developing dyskinesia, hypotension, and impulse control disorders. Serious side effects may arise when used with other antidepressants or sympathomimetics, hence concomitant use should be avoided. Additionally, this medication can cause drowsiness or sudden sleep onset, so caution is required when driving or operating machinery. Women who are pregnant or breastfeeding should use this medication with caution, and its safety in children has not been established. In case of overdose, serious symptoms such as hypertensive crisis and serotonin syndrome may occur, and immediate medical assistance should be sought. This medication should be stored in a cool place away from direct sunlight and kept out of reach of children.

Side effects

  • Influenza
  • skin cancer
  • leukopenia
  • allergy
  • decreased appetite
  • depression
  • hallucinations
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • neck pain
  • arthritis
  • urgency
  • fever
  • fatigue
  • peripheral edema
  • falls
  • joint pain
  • low back pain
  • cough
  • insomnia
  • upper respiratory infection
  • nausea
  • constipation
  • vomiting
  • xerostomia
  • diarrhea
  • abdominal pain
  • dyspepsia
  • hernia
  • infection
  • gingivitis
  • accidental injury
  • weight loss
  • tendinitis
  • movement disorders
  • drowsiness
  • sensory disturbances
  • ataxia
  • muscle hypertonia
  • myasthenia
  • decreased appetite
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • orthostatic hypotension
  • petechiae
  • bleeding
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorders
  • hypertension
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive spending or buying
  • binge eating
  • compulsive eating
  • hypotension
  • excessive drowsiness
  • acute renal failure
  • malignant hyperthermia
  • systemic weakness
  • pulmonary tuberculosis
  • semicoma
  • mobility impairment
  • oculomotor seizures
  • facial paralysis
  • spinal canal stenosis
  • worsening of Parkinson's disease
  • subdural hematoma
  • pneumonia
  • vertebral fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • back pain
  • knee joint replacement
  • herniated disc
  • hypoglycemia
  • weight loss
  • dysuria
  • hematuria
  • frequent urination
  • low urine volume
  • nocturia
  • urinary incontinence
  • vaginitis
  • conjunctival injection
  • diplopia
  • visual impairment
  • skin hypertrophy
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • reflux gas
  • excessive salivation
  • irritable bowel syndrome
  • fissured tongue
  • increased bowel movements
  • unspecified intestinal disease
  • esophagitis
  • hyperacidity
  • gastroesophageal reflux
  • gastric irritation
  • gastritis
  • intestinal motility disorders
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • fainting
  • periorbital edema
  • facial flushing
  • pain
  • delirium
  • sleep disorders
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorder
  • skin paresthesia
  • tremor
  • freezing phenomena
  • limb shaking
  • paroxysmal kinesigenic dyskinesia
  • leg cramps
  • hyperdefecation
  • tremor
  • stuttering
  • voice disorder
  • vocal cord paralysis
  • speech disorder
  • pruritus
  • urticaria
  • boils
  • hair loss
  • contusion
  • sputum abnormalities
  • increased sputum
  • cold
  • bronchitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a sealed container to avoid exposure to air and moisture. It is advisable to store the medication in a cool place between 1 to 25 degrees Celsius.

Appearance and packaging

Appearance

White or almost white, flat round tablet with beveled edges

Package unit

30 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.