Rafutil Tablet 10mg (Lafutidine)

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials of up to 8 weeks of treatment, most ulcers healed within 8 weeks, although healing time may occasionally vary between patients. 2. Short-term treatment of duodenal ulcers: The usual dose is lafutidine 10mg orally twice daily, in the morning and at bedtime. In clinical trials of up to 6 weeks of treatment, most ulcers healed within 6 weeks, although healing time may occasionally vary between patients. 3. Improvement of gastric mucosal lesions in acute gastritis and chronic gastritis: The usual dose is lafutidine 10mg orally once daily at bedtime. In clinical trials of up to 2 weeks of treatment, most lesions healed within 2 weeks, although healing time may occasionally vary between patients. 4. Antibiotic combination therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 or 14 days. 5. Premedication for anesthesia: The usual dose is lafutidine 10mg per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer lafutidine 10mg per dose twice daily.

This medicine should not be used in patients who are allergic to any component of this medicine. It contains lactose, so patients with lactose intolerance or specific metabolic disorders should not take it. Individuals allergic to soybean oil, soy, or peanuts should also avoid this medicine. Patients with a history of drug allergies, those with liver or kidney problems, patients undergoing dialysis, elderly patients, and those with lipid metabolism disorders should use this medicine with caution. It can rarely cause serious allergic reactions, liver function abnormalities, or reductions in blood cells, so if any symptoms occur, discontinue use immediately and seek medical attention. Various mild side effects have been reported in multiple systems including the gastrointestinal, central nervous, and circulatory systems, so one must carefully observe changes in their physical condition. Especially in cases where gastric cancer or malignant tumors are suspected, accurate examinations should be conducted before using this medicine, and it should be discontinued if cancer is confirmed. During treatment, blood, liver, and kidney function tests should be done regularly, and the condition should be closely monitored. Elderly patients or those on dialysis may experience increased blood concentrations of this medicine, so careful adjustments in dosage and intervals are necessary. Pregnant women should only take this medicine under a doctor's judgment if absolutely necessary, and breastfeeding women are advised to avoid this medicine as it may be excreted in breast milk. The safety in children has not been established, so use in pediatric patients is not recommended. This medicine should be kept out of the reach of children and stored in its original container to prevent misuse or degradation of quality.

• Shock
• symptoms of anaphylaxis: facial pallor
• low blood pressure
• generalized rash
• shortness of breath
• liver function impairment
• jaundice
• agranulocytosis
• pharyngitis
• generalized malaise

This medicine should be stored in a sealed container to prevent air or moisture intrusion, and it is safe to store at a temperature between 1 to 30 degrees Celsius. By storing it this way, the effectiveness of the medicine can be maintained, and degradation can be avoided.

Appearance

White round film-coated tablet

Package unit

For domestic use - 30 tablets/bottle, For domestic use - 300 tablets/bottle