Roxotin Tablet (Loxoprofen Sodium Hydrate)

Adult dose

1. For indications 1 and 2: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally three times a day. For single dose therapy, administer 60–120 mg orally. 2. For indication 3: Adults: Administer 60 mg of loxoprofen sodium (anhydrous) orally. Generally, it can be taken twice a day, with a maximum daily dose of 180 mg. It is preferable to avoid taking on an empty stomach.

This medication may cause gastrointestinal bleeding if taken by individuals who regularly consume more than three alcoholic drinks a day, so it is essential to consult a doctor or pharmacist. This medication can affect the cardiovascular system, so caution is needed for patients with a risk of heart disease or stroke, and if cardiovascular symptoms occur, immediate consultation with a doctor is recommended. As it may increase the risk of ulcers or bleeding in the gastrointestinal tract, patients with a history of gastrointestinal disorders or the elderly should be especially cautious, and if abnormal symptoms appear, the medication should be discontinued immediately and treatment sought. This medication should not be used by certain patients such as those with peptic ulcers, severe blood disorders, liver dysfunction, kidney dysfunction, heart failure, pregnant women in late pregnancy, or nursing mothers. If adverse reactions occur during the use of this medication, such as rash, itching, shortness of breath, severe abdominal pain, vomiting, or blood in the stool, the medication should be discontinued immediately and medical assistance sought. For long-term use, regular blood tests and liver and kidney function tests are recommended, and if any abnormal signs are identified, discontinuation of the medication may be necessary. This medication should not be taken with other non-steroidal anti-inflammatory drugs and may interact with specific blood pressure medications, diuretics, anticoagulants, and others. Patients should inform their doctor if they are taking any other medications. Women who are pregnant or may become pregnant should consult a doctor before using this medication and should not take it in late pregnancy. Safety in children has not been established, so it is advisable not to use it in children. Care should be taken in the elderly as the risk of side effects is higher, and the medication should be kept out of reach of children.

Serious side effects

Hives, severe swelling (edema), tightness in the chest, difficulty breathing, shock, anaphylaxis-like symptoms, peptic ulcers, perforation, hematemesis, melena, shock, intestinal perforation, severe skin adverse reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), liver dysfunction (including jaundice), fulminant hepatitis, acute renal failure, interstitial nephritis, shortness of breath, interstitial pneumonia, asthma attacks, tightness in the chest, severe edema, congestive heart failure.

Mild side effects

Occasionally rash, itching, fever, abdominal pain, discomfort in the upper abdomen, loss of appetite, nausea, vomiting, diarrhea, constipation, chest warmth, indigestion, stomatitis, dry mouth, abdominal distension, drowsiness, numbness, dizziness, headache, anemia, eosinophilia, swelling, chest pain, anxiety, fatigue, palpitations, hematuria, proteinuria, fever, relief, abnormal chest X-ray findings, eosinophilia, polymorphic erythema, acute generalized exanthematous pustulosis, skin and subcutaneous tissue disorders.

This medication is susceptible to air and moisture, so it should be stored in a tightly sealed container. It is also advisable to keep it away from direct sunlight and store it at room temperature.

Appearance

White to light yellow round tablets

Package unit

30 tablets/bottle, 300 tablets/bottle