Medication info

Duoact Tablet 5/20 Milligrams

Prescription medicationTablet경구Expired
Ingredient · strength
Atorvastatin›20.72mg / 1 tabletAmlodipine Besylate›6.94mg / 1 tablet
Manufacturer / importer
안국뉴팜(주)
Appearance
White oval film-coated tablet
Packaging
30 tablets/bottle
Approval status
Expired

MFDS item code 202003516 · Approved 2020.05.15

This product's status changed to Expired on 2025.05.15. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
(Hypertension, Angina) Decrease in cardiovascular risk and improvement in dyslipidemia
Who takes it
Adults
Adult dose
This medication is administered only to adults, and the dosages should be individualized based on the efficacy and tolerability of amlodipine/atorvastatin for each patient. ♦ Amlodipine (Esamlodipine) Adults: Amlodipine (Esamlodipine) is to be taken orally once daily at a dose of 5 (2.5) mg, which can be increased up to 10 (5) mg daily based on the patient's response. Adjust dosage appropriately according to symptoms. ♦ Atorvastatin

Ingredients

Manufacturer
안국뉴팜(주)

Efficacy & effects

(Hypertension, Angina) Decrease in cardiovascular risk and improvement in dyslipidemia

  • Hypertension
  • fixed obstruction of coronary arteries
  • vasospasm
  • vascular constriction
  • myocardial ischemia
  • angina
  • coronary heart disease
  • myocardial infarction
  • stroke
  • chronic stable angina
  • type 2 diabetes
  • congestive heart failure
View approved original text

This medication is used for patients who need to take both amlodipine and atorvastatin simultaneously. Amlodipine improves symptoms of myocardial ischemia due to coronary artery disease such as hypertension and stable or variant angina, and reduces the risk of hospitalization for angina in patients with coronary artery disease without heart failure. Atorvastatin decreases the risk of myocardial infarction, stroke, and vascular procedures in patients with various cardiovascular risk factors. It also improves hypercholesterolemia and dyslipidemia and helps reduce risks associated with heart failure and angina. The combination of these two medications is used to effectively manage hypertension and cardiovascular risk factors for the prevention and treatment of cardiovascular diseases.

How to take

Adult dose

This medication is administered only to adults, and the dosages should be individualized based on the efficacy and tolerability of amlodipine/atorvastatin for each patient. ♦ Amlodipine (Esamlodipine) Adults: Amlodipine (Esamlodipine) is to be taken orally once daily at a dose of 5 (2.5) mg, which can be increased up to 10 (5) mg daily based on the patient's response. Adjust dosage appropriately according to symptoms. ♦ Atorvastatin

Precautions

This medication should not be administered to certain patients. For example, it should not be used in individuals who have had allergic reactions to this medication or its components, those with severe liver dysfunction, pregnant women or women of childbearing potential, breastfeeding women, individuals with muscle disorders, patients with severe aortic stenosis, patients in shock, and those who have recently experienced a myocardial infarction. Moreover, patients with severely impaired kidney function, the elderly, individuals with a history of alcohol abuse or liver disease, and those at high risk of muscle damage should use this medication with caution. This medication is primarily used to lower blood pressure and control cholesterol levels, and it is generally well-tolerated; however, mild side effects like flushing, fatigue, edema, dizziness, headache, and dyspepsia may occur. Rarely, severe side effects such as myalgia, liver dysfunction, and allergic reactions may arise, so if any abnormal symptoms occur, the patient should consult a healthcare professional promptly. It is important to undergo regular liver function tests while taking this medication, especially for those with a history of liver disease. Pregnant or breastfeeding women should not use this medication, and women of childbearing potential should employ appropriate contraception. Additionally, this medication may interact with other drugs, so if the patient is taking any other medications, they must inform their healthcare provider. In case of overdose, symptoms such as hypotension, increased heart rate, and shock may occur; thus, appropriate medical attention should be sought immediately. Finally, the safety for children and the elderly has not been adequately established, which necessitates special care. This medication should be kept out of reach of children, and it is advisable not to transfer it to other containers.

Side effects and when to seek care immediately

Serious side effects

Hives, severe swelling (edema), difficulty breathing, angioedema, toxic epidermal necrolysis, severe allergic reactions, severe rash associated with fever, blisters, peeling skin, oral/ocular mucosal pain, severe skin reactions, shortness of breath or respiratory difficulty, asthma attacks, respiratory abnormalities with cough and fever, jaundice (yellowing of skin or eyes), profound lethargy, liver abnormalities (jaundice), sudden and severe headache

Mild side effects

  • Flushing
  • fatigue
  • edema
  • palpitations
  • dizziness
  • headache
  • drowsiness
  • abdominal pain
  • nausea
  • weakness
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  • lethargy
  • pain
  • weight gain/loss
  • hypotension
  • vasculitis
  • muscle rigidity
  • sensory loss/paresthesia
  • peripheral neuropathy
  • syncope
  • altered taste
  • tremor
  • extrapyramidal disorder
  • erectile dysfunction
  • gynecomastia
  • changes in bowel habits
  • dry mouth
  • dyspepsia
  • gingival hyperplasia
  • gum hypertrophy
  • pancreatitis
  • vomiting
  • hyperglycemia
  • arthralgia
  • low back pain
  • muscle cramps

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from exposure to air and moisture. The recommended storage temperature is between 15 and 30 degrees Celsius. Proper storage will help maintain the medication's effectiveness over time.

Appearance and packaging

Appearance

White oval film-coated tablet

Package unit

30 tablets/bottle

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.