Ratiq 10mg (Lafutidine)

Adult dosage

1. Short-term treatment of gastric ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 8 weeks, most ulcers healed within 8 weeks; however, the healing period may vary among patients. 2. Short-term treatment of duodenal ulcers: The usual dose is 10mg of lafutidine orally twice daily, in the morning and at bedtime. In clinical trials in which treatment was given for up to 6 weeks, most ulcers healed within 6 weeks; however, the healing period may vary among patients. 3. Improvement of gastric mucosal lesions in acute and chronic gastritis: The usual dose is 10mg of lafutidine orally once daily at bedtime. In clinical trials in which treatment was given for up to 2 weeks, most lesions healed within 2 weeks; however, the healing period may vary among patients. 4. Concomitant antibiotic therapy for patients with peptic ulcers infected with Helicobacter pylori: Administer lafutidine 20mg, clarithromycin 500mg, and amoxicillin 1000mg twice daily for 7 days or 14 days. 5. Premedication before anesthesia: The usual dose is 10mg of lafutidine per dose, administered orally twice (at bedtime on the day before surgery and 2 hours before anesthesia on the day of surgery). 6. Treatment of reflux esophagitis: Administer 10mg of lafutidine per dose orally twice daily.

This drug should not be used in patients who are allergic to certain ingredients. Additionally, as this drug contains lactose, patients with a genetic inability to digest lactose should not take it. Patients with a history of drug allergies, liver or kidney function problems, patients undergoing dialysis, and elderly patients should use this drug with caution. This medication may cause severe allergic reactions such as anaphylaxis; if symptoms such as facial pallor, low blood pressure, skin redness, or difficulty breathing occur, the patient should immediately stop taking it and seek medical assistance. As liver function abnormalities or jaundice symptoms may occur, regular liver function tests should be conducted, and if abnormalities are detected, administration should be stopped. A decrease in blood cell counts may occur leading to agranulocytosis or thrombocytopenia; if symptoms such as sore throat, body aches, or fever arise, the patient should consult a doctor immediately. Rarely, serious side effects such as skin rashes, seizures, nephritis, and heart problems have been reported; if these symptoms occur, the patient should inform the healthcare provider immediately. Gastrointestinal side effects such as constipation, diarrhea, nausea, vomiting, abdominal bloating, and loss of appetite may occur, while central nervous system side effects such as headaches, insomnia, and drowsiness may also happen. Due to decreased physical functions in the elderly, dosage and administration intervals should be adjusted, and their condition should be closely monitored. Dialysis patients may experience increased plasma drug concentrations, so treatment should start with a low dose and be administered cautiously. Pregnant women or women who may become pregnant should take this medication only if the benefits outweigh the risks as determined by a physician; nursing mothers should avoid taking this drug as it may be secreted in breast milk. In children, safety has not been sufficiently established, so caution is required when using this drug. This medication should be kept out of reach of children and stored in its original container to prevent misuse or degradation in quality. If symptoms suggestive of malignant tumors occur, this medication may alleviate symptoms or delay diagnosis; therefore, tests such as endoscopy should confirm the presence of malignant tumors. If no effect is observed during treatment, it is advisable to switch to another therapy and regularly conduct blood tests along with liver and kidney function tests to check for abnormalities.

• Shock
• anaphylactic symptoms
• facial pallor
• hypotension
• generalized rash
• shortness of breath
• liver dysfunction
• jaundice
• agranulocytosis
• pharyngitis

This medication should be stored in a tightly closed container to prevent exposure to air and moisture. It is recommended to keep the storage temperature between 1 and 30 degrees Celsius.

Appearance

White round film-coated tablets

Package unit

30 tablets/bottle, 300 tablets/bottle