Medication info
Famotidine 20 mg (Famotidine)

Famotidine 20 mg (Famotidine)

Prescription medicationTablet경구
Ingredient · strength
Famotidine›20mg / 1 tablet
Manufacturer / importer
에이치엘비제약(주)
Appearance
Light green, round film-coated tablet
Packaging
30 tablets/bottle, 300 tablets/bottle
Approval status
Active

MFDS item code 202003282 · Approved 2020.05.06 · Insurance code 647303940

Summary

Main use
Improvement of gastric ulcers and upper gastrointestinal bleeding, improvement of gastric mucosal lesions (erosion, bleeding, etc.)
Who takes it
Adults
Adult dose
Gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, Zollinger-Ellison syndrome: As famotidine, 20 mg orally twice daily (after breakfast, after dinner, or at bedtime) or 40 mg orally once daily (at bedtime). For cases of upper gastrointestinal bleeding, treatment generally begins with an injection, which is switched to oral administration once possible. Acute gastritis, acute exacerbation of chronic gastritis:

Ingredients

Manufacturer
에이치엘비제약(주)

Efficacy & effects

Improvement of gastric ulcers and upper gastrointestinal bleeding, improvement of gastric mucosal lesions (erosion, bleeding, etc.)

  • Gastric and duodenal ulcers
  • anastomotic ulcers
  • upper gastrointestinal bleeding
  • acute stress ulcers
  • hemorrhagic gastritis
  • gastroesophageal reflux disease
  • Zollinger-Ellison syndrome
  • gastric mucosal lesions
  • erosion
  • bleeding
  • redness
  • swelling
View approved original text

This medication is used for various conditions related to gastric and duodenal ulcers, anastomotic ulcers, and upper gastrointestinal bleeding. It is particularly helpful in treating bleeding caused by peptic ulcers, acute stress ulcers, and hemorrhagic gastritis. It is also effective for gastroesophageal reflux disease and Zollinger-Ellison syndrome. It improves symptoms such as erosion, bleeding, redness, and swelling of the gastric mucosa that appear during acute exacerbation of acute and chronic gastritis. It is used to enhance the gastric health of patients by improving mucosal lesions in various gastrointestinal diseases.

How to take

Adult dose

Gastric and duodenal ulcers, anastomotic ulcers, upper gastrointestinal bleeding, gastroesophageal reflux disease, Zollinger-Ellison syndrome: As famotidine, 20 mg orally twice daily (after breakfast, after dinner, or at bedtime) or 40 mg orally once daily (at bedtime). For cases of upper gastrointestinal bleeding, treatment generally begins with an injection, which is switched to oral administration once possible. Acute gastritis, acute exacerbation of chronic gastritis:

Precautions

This medication should not be used in certain patients. Individuals allergic to the ingredients of this medication or similar drugs should not take it. Also, this medication contains lactose, so individuals with genetic issues that hinder lactose digestion should avoid using it. There are cases where caution is required when using this medication. Patients with a history of drug allergies should be careful, and those with poor kidney function may require a dose reduction or extended dosing intervals due to the potential for higher drug concentrations. Patients with heart diseases may need to be cautious of cardiac-related side effects. Individuals with poor liver function should also be careful as symptoms may worsen, and older adults should use it cautiously as kidney function decline is more likely. This medication can rarely cause serious side effects. Allergic reactions such as shock, respiratory distress, facial or neck swelling, and hives may occur, and if any unusual symptoms arise, the medication should be stopped immediately and treatment sought. There may be a decrease in blood cell counts or blood abnormalities such as anemia and thrombocytopenia, necessitating regular blood tests. Risks of severe skin reactions, liver dysfunction, rhabdomyolysis, cardiac rhythm abnormalities, consciousness disorders, seizures, nephritis, pneumonia, etc., are present, so if such symptoms manifest, the medication should be stopped immediately and medical attention should be obtained. When using this medication, treatment progress should be closely monitored, and it should be used in the minimum effective dose. If no therapeutic effect is observed, it is advisable to switch to another treatment option. Routine checks on blood tests, liver function tests, and kidney function tests should be conducted. Patients undergoing dialysis should be cautious when using this medication alongside specific phosphate binders, as it may reduce the efficacy of the medication. This medication may interact with other drugs. In particular, taking it with certain antifungal agents or specific anticancer drugs may diminish the effectiveness of this medication or others, hence consulting with a physician or pharmacist is necessary. Older adults should be careful as kidney function may be reduced, leading to longer retention of the drug in the body; thus, doses should be reduced or intervals extended for cautious use. Women who are pregnant or may become pregnant should carefully weigh the benefits and risks of using this medication. Additionally, since this medication can be passed through breast milk, it is safer for nursing mothers to discontinue breastfeeding. The safety of this medication in pediatric patients has not been adequately verified, so it should be used cautiously in children. Finally, this medication can mask symptoms of gastric cancer, so it should only be used after confirming that it is not gastric cancer.

Side effects and when to seek care immediately

Serious side effects

Shock, hypersensitivity (anaphylaxis, respiratory distress, generalized flushing, angioedema [facial or pharyngeal edema, etc.], hives), pancytopenia, agranulocytosis, aplastic anemia, hemolytic anemia, thrombocytopenia (general malaise, weakness, subcutaneous or mucosal bleeding, fever, etc.), Stevens-Johnson syndrome (mucocutaneous syndrome), Lyell syndrome (toxic epidermal necrolysis), liver dysfunction, jaundice, rhabdomyolysis (hyperkalemia, myoglobinuria, serum muscle

Mild side effects

  • Rash
  • hives (erythema)
  • facial swelling
  • leukopenia
  • eosinophilia
  • constipation
  • diarrhea
  • thirst
  • nausea
  • vomiting
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  • abdominal bloating
  • loss of appetite
  • stomatitis
  • elevated blood pressure
  • flushing
  • tinnitus
  • bradycardia
  • tachycardia
  • atrioventricular block
  • bronchospasm
  • elevated AST (GOT)/ALT (GPT)/ALP
  • elevated total bilirubin/LDH
  • liver function abnormality
  • hepatitis
  • general malaise
  • lethargy
  • headache
  • drowsiness
  • insomnia
  • hallucination

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to protect it from air and moisture. It is also recommended to store the medication at room temperature, ideally between 1 and 30 degrees Celsius, avoiding extremes of cold or heat.

Appearance and packaging

Appearance

Light green, round film-coated tablet

Package unit

30 tablets/bottle, 300 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.