Genbrex Capsule 100mg (Celecoxib)

Adult dose

The minimum recommended dose of this medicine should be adjusted for each patient and may be administered with or without food. ○ Adults 1. Osteoarthritis (degenerative arthritis) : Take 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. 2. Rheumatoid arthritis : Take 100 mg or 200 mg of celecoxib per dose twice daily. 3. Ankylosing spondylitis (AS) : Administer 200 mg of celecoxib once daily, or divide the dose into 100 mg twice daily. If no effect is observed after 6 weeks, the dose may be increased to 400 mg per day. If no effect is observed after 6 weeks of treatment with 400 mg per day, other treatment options should be considered. 4. Acute pain and primary dysmenorrhea : The initial recommended dose is 400 mg of celecoxib, with an additional 200 mg on the first day of treatment if needed. From the second day of treatment, the recommended dose, if needed, is 200 mg per dose twice daily. ○ Patients with hepatic impairment : In patients with moderate hepatic impairment (Child-Pugh Class II), the dose should be reduced to approximately 50% of the recommended daily dose.

This medication may increase the risk of gastrointestinal bleeding in individuals who regularly consume more than three drinks a day, so it is essential to consult with a doctor or pharmacist. This drug can increase the risk of thrombotic events such as cardiovascular diseases, myocardial infarction, and stroke, and should only be used at the lowest effective dose for the shortest duration. If any cardiovascular symptoms occur, seek medical attention immediately. Gastrointestinal complications such as ulcers, bleeding, and perforation may occur, especially in elderly patients or those with a history of gastrointestinal disorders, and caution is required. This medication should not be used in patients with specific allergy histories, severely impaired liver or kidney function, active gastrointestinal bleeding, severe cardiovascular disease, pregnant or nursing women. Patients with impaired liver or kidney function, asthma, heart failure, or hypertension should use this medication cautiously, especially elderly patients. There may be various side effects associated with this medication, including dyspepsia, headache, dizziness, rash, swelling, elevated blood pressure, gastrointestinal bleeding, liver dysfunction, and decreased kidney function, so consult a doctor immediately if any symptoms occur. This drug is metabolized in the liver, so dose adjustments may be necessary when taken with other medications that affect liver function. Women who are pregnant or may become pregnant should not take this medication, and nursing mothers should consider discontinuing breastfeeding while taking this drug. The safety of this drug in children and adolescents has not been established, so its use is not recommended. While taking this medication, regular blood tests, liver function tests, and kidney function tests should be performed to detect and address abnormal signs early. In case of overdose, symptoms such as lethargy, nausea, vomiting, and gastrointestinal bleeding may occur, so immediate medical attention should be sought. Keep this medication out of reach of children and ensure it is not transferred to other containers.

Gastrointestinal bleeding, cardiovascular thrombotic response, myocardial infarction, stroke, perforation of the upper and lower gastrointestinal tract, ulcer, bleeding, bronchitis, sinusitis, upper respiratory tract infection, urinary tract infection, pharyngitis, rhinitis, anemia, thrombocytopenia, hypersensitivity, insomnia, anxiety, confusion, dizziness, muscle tension, drowsiness, blurred vision, tinnitus, palpitations, congestive heart failure, arrhythmia, tachycardia, hypertension, flushing, cough, vomiting, abdominal pain, diarrhea, dyspepsia, bloating, gastric ulcer, dental disease, duodenal ulcer, esophageal ulcer, intestinal perforation, pancreatitis, elevated liver enzymes, itching, rash, hives, petechiae, angioedema, alopecia, bullous dermatitis, peripheral edema, facial edema, influenza-like illness, injury, headache, leg cramps, muscle tension, sensory depression, migraine, neuralgia, neuropathy, sensory abnormalities, cerebral infarction, aseptic meningitis, ataxia, suicide, loss of smell, loss of taste, allergy exacerbation, allergic reaction, weakness, chest pain, fluid retention, systemic edema, facial edema, fatigue, lethargy, fever, facial flushing, influenza-like syndrome, pain, peripheral pain, sepsis, sudden death, anaphylactic-like reaction, angioedema, loss of appetite, increased appetite, depression, neurological hyperreactivity, drowsiness, fatal intracranial hemorrhage, hallucinations, exacerbation of epilepsy, upper respiratory tract infection, bronchial spasm, exacerbation of bronchial spasm, shortness of breath, laryngitis, pneumonia, nosebleed, voice disorders, vesicular dermatitis, dermatitis, nail disease, photosensitive reaction, erythematous rash, rash with maculopapular lesions, skin disease, dry skin, increased sweating, erythema multiforme, exfoliative dermatitis, Stevens-Johnson syndrome, toxic epidermal necrolysis, eczema, lipoma, allergic dermatitis, petechiae, dandruff, drug rash with eosinophilia and systemic symptoms, arrhythmia, ventricular hypertrophy, angina pectoris, unstable angina, coronary artery disorder, myocardial infarction, heart failure, palpitations, tachycardia, aortic valve insufficiency, hematoma, bradycardia, syncope, ventricular fibrillation, pulmonary embolism, cerebral vascular accident, peripheral necrosis, thrombophlebitis, vasculitis, deep vein thrombosis, cerebral hemorrhage, duodenal ulcer, wound infection, gingivitis, herpes simplex, shingles, bacterial infection, fungal infection, soft tissue infection, viral infection, candidiasis, genital candidiasis, otitis media, breast pain, menopausal symptoms, fibrocystic breast disease, thoracic neoplasm, chest pain, dysmenorrhea, menstrual disorders, vaginal bleeding, vaginitis, prostate disorders, ovarian cysts, hearing loss, ear abnormalities, otalgia, hearing impairment, liver dysfunction, elevated ALT, elevated AST, increased γ-GTP, increased ALP, positive urobilinogen, cholelithiasis, hepatitis, jaundice, liver failure, fulminant hepatitis, liver necrosis, increased serum sodium, increased serum potassium, elevated BUN, increased CPK, diabetes, hypercholesterolemia, hyperglycemia, hypokalemia, hyperkalemia, elevated NPN, increased creatinine, increased alkaline phosphatase, weight gain, loss of appetite, elevated LDH, hypoglycemia, hyponatremia, synovial sac, arthralgia, arthrosis, skeletal abnormalities, myalgia, cervical rigidity, synovitis, tendinitis, myositis, fracture, tendon rupture, back pain, muscle rigidity, decreased hematocrit, increased hemoglobin, petechiae, nosebleed, thrombocytopenia, anemia, agranulocytosis, aplastic anemia, pancytopenia, leukopenia, granulomatous inflammation, contact dermatitis, injection site reactions, skin nodules, taste disturbance, albuminuria, cystitis, hematuria, dysuria, polyuria, kidney stones, urinary incontinence, urinary tract infection, blurred vision, cataract, conjunctivitis, eye pain, glaucoma, retinal artery or vein occlusion, increased serum creatinine, increased β2-microglobulin, increased NAG, positive urine hematuria, positive urine protein, renal dysfunction, acute renal failure, interstitial nephritis, anaphylactic reaction, vasculitis, pulmonary embolism, interstitial pneumonia, hepatitis, photosensitive reaction, Stevens-Johnson syndrome, erythema multiforme, toxic epidermal necrolysis, acute generalized pustular dermatitis, exfoliative dermatitis, acute renal failure, hyponatremia, tubular interstitial nephritis, nephrotic syndrome, focal segmental glomerulosclerosis, menstrual disorders, female infertility, chest pain, lethargy, drowsiness, nausea, upper abdominal pain, gastrointestinal bleeding, hypertension, acute renal failure, respiratory depression, coma, thirst, ulcerative stomatitis, gastritis, allergy, back pain, hyperlipidemia, diabetes, weight gain, fracture, arthralgia, positive RA factor, pneumonia, shortness of breath, elevated ALT, hearing impairment

Store this medication in a tightly sealed container to prevent air or moisture from entering. It is recommended to maintain storage temperatures between 15 and 30 degrees Celsius.

Appearance

A white capsule filled with powder that is white to light yellow, with a blue stripe on the upper and lower sides.

Package unit

30 capsules/bottle, 100 capsules/bottle