Medication info
Zocorlin Tablet 10/10 mg

Zocorlin Tablet 10/10 mg

Prescription medicationTablet경구
Ingredient · strength
Ezetimibe›10mg / 1 tabletSimvastatin›10mg / 1 tablet
Manufacturer / importer
(주)다산제약
Appearance
Biconvex rectangular tablets that are white to light yellow.
Packaging
30 tablets/box [10 tablets/PTP x 3]
Approval status
Active

MFDS item code 202003232 · Approved 2020.04.29 · Insurance code 660703440

Summary

Main use
Treatment for improving cholesterol and lipid levels in hypercholesterolemia (primary, homozygous familial) and mixed hyperlipidemia.
Who takes it
Adults
Adult dose
This medication should be taken once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg, with the generally recommended starting dose being 10/20 mg daily. For patients who have less need to reduce LDL-cholesterol, treatment can begin with 10/10 mg daily. After starting the medication or adjusting the dosage, lipid levels should be measured at least 4 weeks apart to make adjustments.

Ingredients

Manufacturer
(주)다산제약

Efficacy & effects

Treatment for improving cholesterol and lipid levels in hypercholesterolemia (primary, homozygous familial) and mixed hyperlipidemia.

  • Primary hypercholesterolemia
  • heterozygous familial hypercholesterolemia
  • non-familial hypercholesterolemia
  • mixed hyperlipidemia
  • homozygous familial hypercholesterolemia
  • elevated total cholesterol
  • elevated LDL-cholesterol
  • elevated apolipoprotein B
  • elevated triglycerides
  • increased risk of atherosclerotic vascular disease due to hypercholesterolemia
  • dyslipidemia
  • diabetes
View approved original text

This medication helps lower blood cholesterol levels in patients with primary hypercholesterolemia and homozygous familial hypercholesterolemia, particularly reducing bad LDL cholesterol, apolipoprotein B, and triglycerides, while increasing good HDL cholesterol. It is also used as an adjunct therapy to diet in patients with mixed hyperlipidemia. This medication is primarily added when non-drug approaches like diet are insufficient. For patients with homozygous familial hypercholesterolemia, it is also used as an adjunct to other lipid-lowering therapies. It is important to identify and manage any underlying conditions causing dyslipidemia, such as diabetes or hypothyroidism, before treatment starts. Appropriate dietary adjustments should be made in conjunction with the medication, and lipid levels should be monitored periodically during treatment. This medication is effectively used to reduce the risks associated with hypercholesterolemia and related atherosclerotic vascular diseases.

How to take

Adult dose

This medication should be taken once daily in the evening, regardless of meals. The dosage range for patients with primary hypercholesterolemia is 10/10 mg to 10/40 mg, with the generally recommended starting dose being 10/20 mg daily. For patients who have less need to reduce LDL-cholesterol, treatment can begin with 10/10 mg daily. After starting the medication or adjusting the dosage, lipid levels should be measured at least 4 weeks apart to make adjustments.

Precautions

This medication may cause serious muscle-related side effects such as myopathy or rhabdomyolysis, so if symptoms like muscle pain or weakness occur, consult a physician immediately. Patients with allergies to any components of this medication or those with active liver disease, as well as pregnant or breastfeeding women, should not take this medication. The risk of muscle side effects increases when this medication is taken with certain strong drugs, so anyone taking other medications must inform their healthcare provider. Elderly patients over 65 years old or those with hypothyroidism or impaired kidney function should be cautious when taking this medication, and regular blood tests to monitor liver function and muscle condition are important. If unexplained muscle pain, tenderness, or weakness occurs while taking this medication, stop immediately and visit a hospital, and it is advisable to regularly check serum creatine kinase levels according to a doctor's instructions. This medication can affect liver function, so those with a history of liver disease or elevated liver function test results should consult a physician and it is advisable to avoid alcohol consumption. Women planning pregnancy or who could become pregnant should consult a physician before taking this medication and must stop it immediately if pregnancy is confirmed. Breastfeeding women are recommended to discontinue breastfeeding when taking this medication due to the risk of transmitting the drug to the baby. Caution should be exercised when administering this medication to children and adolescents, particularly it is not recommended for children under 10 years of age. During the use of this medication, inform other doctors or pharmacists about its use and be cautious when receiving prescriptions for new medications. In case of overdose, as there is no specific antidote, visit a medical institution immediately for treatment based on symptoms. Combining this medication with grapefruit juice may increase serum drug concentrations, raising the risk of side effects, so it is advisable to avoid grapefruit juice.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), liver abnormalities (jaundice), severe allergic reactions, severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis), respiratory issues (shortness of breath), severe neurological symptoms (dizziness, paresthesia, syncope), severe muscle weakness, myopathy/rhabdomyolysis, hepatitis, pancreatitis, thrombocytopenia, drug reaction with eosinophilia and systemic symptoms (DRESS), drug-induced liver injury, severe edema and .

Mild side effects

Headache, diarrhea, influenza, upper respiratory infection, myalgia, limb pain, fatigue, nausea, abdominal pain, constipation, dyspepsia, flatulence, pruritus, rash, asthenia, dizziness, paresthesia, depression, insomnia, sore throat, alopecia, increased serum creatine phosphokinase (CPK), weight loss, hematuria, nocturia.

Not everyone experiences these, and they can vary from person to person.

Storage

This medication is sensitive to air and moisture, so it must be stored in a tightly sealed container. It is important to maintain a storage temperature between 1°C and 30°C.

Appearance and packaging

Appearance

Biconvex rectangular tablets that are white to light yellow.

Package unit

30 tablets/box [10 tablets/PTP x 3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.