Medication info
Akrab Tablet 30/20 mg

Akrab Tablet 30/20 mg

Prescription medicationTablet경구
Ingredient · strength
Fimasartan Potassium Trihydrate Granules›75mg / 1 tabletAtorvastatin Calcium Trihydrate›10.4mg / 1 tablet
Manufacturer / importer
(주)보령
Appearance
Light green round film-coated tablet
Packaging
30 tablets/box [10 tablets/PTP*3]
Approval status
Active

MFDS item code 202003219 · Approved 2020.04.29 · Insurance code 641907650

Summary

Main use
Effectiveness in improving (hypertension, hyperlipidemia) and reducing the risk of myocardial infarction and stroke
Who takes it
Adults
Adult dose
This medication should be taken once daily, 1 tablet, with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). ○ Pimasartan 1. Adults The recommended dosage is 30 to 60 mg once daily, taken regardless of meals. If blood pressure is not well controlled, the dosage may be increased to 120 mg once daily. ○ Atorvastatin 1. Hyperlipidemia The recommended initial dosage is 10 mg of atorvastatin once daily; for patients requiring more LDL cholesterol reduction, it may be started at 20 mg or 40 mg once daily (only when a reduction of 45% or more in LDL cholesterol is required). This medication can be administered in a dosage range of 10 to 80 mg once daily. The initial and maintenance dosages should be individualized based on treatment goals and patient response, and lipid levels should be analyzed within 2 to 4 weeks after starting treatment and/or adjusting dosages to make necessary adjustments.

Ingredients

Manufacturer
(주)보령

Efficacy & effects

Effectiveness in improving (hypertension, hyperlipidemia) and reducing the risk of myocardial infarction and stroke

  • Essential hypertension
  • primary hypercholesterolemia
  • mixed dyslipidemia
  • primary dysbetalipoproteinemia
  • elevated serum triglycerides
  • homozygous familial hypercholesterolemia
View approved original text

This medication is used for patients who need to take two drugs, Pimasartan and Atorvastatin, simultaneously. Pimasartan primarily helps to control blood pressure in patients with essential hypertension. Atorvastatin calcium reduces the risk of cardiovascular events such as myocardial infarction and stroke in patients at high risk of cardiovascular disease, and helps treat hyperlipidemia. In particular, it helps to lower cholesterol levels and increase HDL cholesterol levels in patients with primary hypercholesterolemia and mixed dyslipidemia. The combination of these two drugs is used to effectively manage hypertension and the risk of cardiovascular disease.

How to take

Adult dose

This medication should be taken once daily, 1 tablet, with water regardless of meals. It is recommended to take it at the same time every day (e.g., in the morning). ○ Pimasartan 1. Adults The recommended dosage is 30 to 60 mg once daily, taken regardless of meals. If blood pressure is not well controlled, the dosage may be increased to 120 mg once daily. ○ Atorvastatin 1. Hyperlipidemia The recommended initial dosage is 10 mg of atorvastatin once daily; for patients requiring more LDL cholesterol reduction, it may be started at 20 mg or 40 mg once daily (only when a reduction of 45% or more in LDL cholesterol is required). This medication can be administered in a dosage range of 10 to 80 mg once daily. The initial and maintenance dosages should be individualized based on treatment goals and patient response, and lipid levels should be analyzed within 2 to 4 weeks after starting treatment and/or adjusting dosages to make necessary adjustments.

Precautions

This medication may cause serious harm or death to the fetus and newborn if taken during pregnancy, especially in the second and third trimesters. Therefore, use should be discontinued immediately upon confirmation of pregnancy. This medication should not be used in patients with impaired liver function, muscle disease, or certain genetic lactose intolerance. Patients with a history of alcohol abuse or liver disease, the elderly, and those with impaired kidney function should take this medication with increased caution, and close monitoring by a physician may be required if necessary. This medication may cause muscle-related side effects such as myalgia, muscle weakness, and muscle damage; therefore, if severe or persistent muscle pain occurs, the physician should be notified immediately. Since this medication may cause blood pressure to drop too low, if symptoms of hypotension occur, immediate consultation with healthcare professionals is advised, especially for patients taking diuretics who should be particularly careful. During the use of this medication, regular liver function tests and blood tests are important to check for liver damage or muscle damage. Interactions may occur when taken with other medications, so it is essential to inform the physician or pharmacist of any other medications being taken. This medication may cause drowsiness or dizziness when driving or operating dangerous machinery, so caution is necessary. Women planning to become pregnant should consult a physician before taking this medication and should use appropriate contraception. Breastfeeding women should discuss with the physician whether to discontinue breastfeeding or the medication, as this medication may affect the baby. Safety and efficacy in children and adolescents under 18 years have not been established, and use should be avoided. In case of overdose, symptoms such as hypotension, palpitations, and bradycardia may occur, and immediate emergency treatment should be sought. This medication should be kept out of reach of children and stored in its original container to prevent misuse or degradation in quality.

Side effects and when to seek care immediately

Serious side effects

Urticaria, severe swelling (edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with fever, blisters, peeling skin, pain in oral/ocular mucosa, shortness of breath or difficulty breathing, asthma attacks, respiratory abnormalities accompanied by cough and fever, yellowing of the skin or eyes (jaundice), extreme lethargy, sudden and severe headaches, thunderclap headaches, seizures, confusion, visual disturbances, paralysis, urination

Mild side effects

Headache, dizziness, fainting, sedation, migraine, dyspepsia, vomiting, nausea, abdominal pain, weakness, foreign body sensation, abnormal liver enzyme levels, increased lactate dehydrogenase (LDH) levels, hypokalemia, fatigue, swelling, myalgia, hypertension, ventricular extrasystoles, cough, itching, localized urticaria, facial flushing, flushing, erectile dysfunction, decreased platelet count, abnormal liver function tests, increased CK levels in the blood, positive leukocytes in the urine,

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly sealed container to protect it from air and moisture. It is also recommended to store it at room temperature between 1 degree and 30 degrees Celsius. Avoid very hot or very cold places.

Appearance and packaging

Appearance

Light green round film-coated tablet

Package unit

30 tablets/box [10 tablets/PTP*3]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.