Careamin Injection

Adult dosage

For adults, intravenous drip infusion of 1 to 1.5 g of total amino acids per kg of body weight per day is the maximum dosage. The infusion rate should ideally result in a concentration of about 10 g of total amino acids over 60 minutes, and the principle is to administer 25 drops over 1 minute.

Children's dosage

In children, dosage and infusion rates should be adjusted.

This medication must be used strictly according to a physician's instructions and should not be self-administered or discontinued arbitrarily. It should not be administered to patients in hepatic coma or at risk of hepatic coma. It should also be avoided in patients with severe renal impairment or high blood nitrogen levels. It is contraindicated for patients with nitrogen metabolism problems or severe heart failure, pulmonary edema, or those with extremely low or no urine output. This medication is also unsuitable for patients with acidosis or excess fluid in the body, low blood potassium levels, and those in shock. Careful administration is necessary for patients with congestive heart failure or liver and kidney dysfunction, and if unusual reactions occur, consult a physician immediately. Rarely, allergic reactions such as skin rashes may occur. If such symptoms arise, the medication should be discontinued. Occasionally, symptoms like nausea, vomiting, chest discomfort, palpitations, rapid heartbeat, and elevated blood pressure may occur. Rapid administration of large amounts can lead to acidosis, requiring caution in the rate and amount of administration. Symptoms such as chills, fever, headache, difficulty breathing, and in severe cases, respiratory arrest or shock may occur, so notify healthcare personnel if any unusual symptoms arise. Various metabolic disturbances like metabolic acidosis, sugar abnormalities, and electrolyte imbalance may occur, necessitating regular check-ups. Patients with impaired liver or kidney function are at risk of elevated waste levels in the blood, necessitating caution. Large doses can affect electrolyte balance, so exercising particular caution when using it alongside other electrolyte supplements is recommended. Co-administration with certain antibiotics (tetracyclines) may reduce effectiveness, so inform your doctor of all medications you are taking. There is no established safety for use in pregnant women, thus it should only be used if the therapeutic benefits outweigh the risks. When administering to children or infants, lower concentrations should be used, and blood ammonia levels must be monitored frequently. Elderly patients may have reduced bodily functions, so the rate of administration should be slowed and the dosage adjusted accordingly. During administration, it should be infused slowly into the vein, as rapid infusion can induce chills or vomiting. The solution should be warmed to body temperature before use, and strict aseptic conditions should be maintained before and after use to reduce the risk of infection. Do not use if the solution is cloudy or discolored, and it should be stored unopened to protect its efficacy.

Serious side effects

• Severe swelling (edema)
• difficulty breathing
• shock
• pallor

Mild side effects

• Rash
• nausea
• vomiting
• chest discomfort
• palpitations
• rapid heartbeat (tachycardia)
• increased blood pressure
• acidosis
• chills
• fever

This medication should be stored in a sealed container to prevent air or moisture ingress. It is recommended to maintain a storage temperature between 1 degree and 30 degrees at room temperature to preserve its efficacy.

Appearance

A clear liquid ranging from colorless to pale yellow, contained in a colorless and transparent glass ampoule for injection.

Package unit

250 milliliters/bottle[X1]