Medication info

Maorect Tablets 1 mg (Rasagiline Mesylate)

Prescription medicationTabletOralExpired
Ingredient · strength
Rasagiline Mesylate›1.56mg / 1 tablet
Manufacturer / importer
Ilhwa Co., Ltd.
Appearance
Flat, round tablet with edges, white or nearly white
Packaging
30 tablets/PTP [(10 tablets/PTP x 3)]
Approval status
Expired

MFDS item code 202003117 · Approved 2020.04.28

This product's status changed to Expired on 2025.04.28. It may no longer be sold, so consult a doctor or pharmacist before taking it.

Summary

Main use
Treatment of idiopathic Parkinson's disease
Who takes it
Adults
Adult dose
This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1 mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5 mg once daily. If the dose is well tolerated but the clinical response is inadequate, it may be increased to 1 mg once daily. This medicine may be taken with or without food.

Ingredients

Manufacturer
Ilhwa Co., Ltd.

Efficacy & effects

Treatment of idiopathic Parkinson's disease

  • Idiopathic Parkinson's disease
  • motor fluctuation symptoms
View approved original text

This medication is used for the treatment of idiopathic Parkinson's disease. In the early stages, it is administered as monotherapy or as an adjunct to dopamine agonists to alleviate symptoms. It also assists in the treatment of motor fluctuations, particularly when there are variations in symptoms after taking medication, supporting levodopa treatment. This contributes to improving motor function and enhancing the quality of daily life for patients with Parkinson's disease.

How to take

Adult dose

This medicine is administered orally once daily to adults as monotherapy or adjunctive therapy. 1) Monotherapy or adjunctive therapy to a dopamine agonist: Administer 1 mg orally once daily. 2) Adjunctive therapy to levodopa: The recommended initial dose for patients taking levodopa is 0.5 mg once daily. If the dose is well tolerated but the clinical response is inadequate, it may be increased to 1 mg once daily. This medicine may be taken with or without food.

Precautions

This medication should not be used in patients with allergies to the active ingredient or any other components. It should not be administered to patients who are taking other MAO inhibitors or certain natural medicines, or who have recently discontinued them within the last 2 weeks. Patients who are taking or have recently discontinued medications such as pethidine, tramadol, or dextromethorphan within the last 2 weeks should not use this medication. It should not be used in patients with moderate to severe hepatic dysfunction. This medication can cause various side effects, with common side effects including headache, dizziness, depression, fever, musculoskeletal pain, dermatitis, etc. Severe side effects such as blood disorders, angina, myocardial infarction, and cerebrovascular accidents have been reported, so if any abnormal symptoms occur, immediate consultation with a healthcare provider is necessary. Drowsiness or sudden sleep may occur while taking this medication, so caution is needed when driving or operating machinery. Moreover, this medication has serious interactions with certain drugs, so it is essential to inform your doctor or pharmacist if you are taking other medications. It can be dangerous, especially when combined with MAO inhibitors, certain analgesics, antidepressants, and sympathomimetics. Caution is required during pregnancy or breastfeeding, and the safety for children has not been established. Elderly patients do not require special dosage adjustments, but patients with impaired liver function should be cautious. In case of overdose, serious symptoms such as hypertensive crisis and serotonin syndrome may occur, requiring immediate medical attention. This medication must be kept out of reach of children and stored in a cool place between 1 and 25 degrees Celsius.

Side effects

  • influenza
  • skin cancer
  • leukopenia
  • allergy
  • loss of appetite
  • depression
  • hallucination
  • headache
  • cerebrovascular accident
  • conjunctivitis
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  • dizziness
  • angina pectoris
  • myocardial infarction
  • rhinitis
  • abdominal distension
  • dermatitis
  • vesicular rash
  • musculoskeletal pain
  • neck pain
  • arthritis
  • urinary urgency
  • fever
  • malaise
  • nausea
  • peripheral edema
  • falls
  • arthralgia
  • low back pain
  • cough
  • insomnia
  • upper respiratory infection
  • orthostatic hypotension
  • constipation
  • vomiting
  • dry mouth
  • diarrhea
  • abdominal pain
  • indigestion
  • hernia
  • infection
  • gingivitis
  • traumatic injury
  • weight loss
  • tenosynovitis
  • movement disorder
  • drowsiness
  • sensory disturbance
  • ataxia
  • muscle tone abnormality
  • myasthenia
  • decreased appetite
  • abnormal dreams
  • respiratory distress
  • rash
  • hyperhidrosis
  • hemorrhagic spots
  • melanoma
  • confusion
  • carpal tunnel syndrome
  • balance disorder
  • hallucination
  • elevated blood pressure
  • pathological gambling
  • increased libido
  • hypersexuality
  • compulsive shopping or buying
  • binge eating
  • compulsive eating
  • hypotension
  • excessive drowsiness
  • acute renal failure
  • spinal fracture
  • rib fracture
  • tendon injury
  • pelvic fracture
  • leg fracture
  • upper limb fracture
  • back pain
  • knee arthroplasty
  • herniated disc
  • hypoglycemia
  • weight loss
  • dysuria
  • orthostatic hypotension
  • malignant hyperthermia
  • systemic weakness
  • pulmonary tuberculosis
  • hallucination
  • semicoma
  • gait disturbance
  • ocular motor seizures
  • facial paralysis
  • spinal canal stenosis
  • worsening of Parkinson's disease
  • subdural hematoma
  • pneumonia
  • myalgia
  • osteoporosis
  • limb weakness
  • concussion
  • unspecified abrasion
  • laceration
  • scoliosis
  • thirst
  • hematuria
  • polyuria
  • vaginitis
  • conjunctival injection
  • diplopia
  • visual impairment
  • skin hypertrophy
  • palpitations
  • arrhythmia
  • gastrointestinal discomfort
  • gastroesophageal reflux
  • excessive salivation
  • irritable bowel syndrome
  • fissured tongue
  • increased bowel movement frequency
  • unspecified gastrointestinal disease
  • esophagitis
  • excessive stomach acid
  • gastroesophageal reflux disease
  • gastric irritation
  • gastroenteritis
  • intestinal motility disorder
  • periodontitis
  • Helicobacter pylori gastritis
  • anemia
  • leg pain
  • chest pain
  • syncope
  • periorbital edema
  • facial flushing
  • pain
  • delirium
  • sleep disorder
  • aggression
  • amnesia
  • memory impairment
  • lethargy
  • sleep talking
  • psychosexual disorder
  • skin tingling
  • tremor
  • freezing phenomenon
  • limb tremors
  • myotonic dystrophy
  • leg cramps
  • polyuria
  • tremors
  • stuttering
  • voice disorder
  • vocal cord paralysis
  • speech disorder
  • localized inflammation
  • pruritus
  • urticaria
  • eyelid skin disorder
  • furuncle
  • hair loss
  • contusion
  • abnormal sputum
  • increased sputum
  • cold
  • bronchitis

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be kept in a tightly sealed container to prevent exposure to air or moisture. A cool place with a storage temperature between 1 degree and 25 degrees Celsius is suitable. Proper storage will help maintain the effectiveness and safety of the medication.

Appearance and packaging

Appearance

Flat, round tablet with edges, white or nearly white

Package unit

30 tablets/PTP [(10 tablets/PTP x 3)]

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.