Medication info
Thioctacid Tablet 480 mg (R-Lipoic Acid Trometamol)

Thioctacid Tablet 480 mg (R-Lipoic Acid Trometamol)

Prescription medicationTabletOral
Ingredient · strength
R-Thioctic Acid Tromethamine›480mg / 1 tablet
Manufacturer / importer
Kunil Biopharm Co., Ltd.
Appearance
Light green, oblong, film-coated tablet
Packaging
30 tablets/bottle, 100 tablets/bottle
Approval status
Active

MFDS item code 202003054 · Approved 2020.04.27 · Insurance code 073000040

Summary

Main use
Relief of diabetic polyneuropathy
Who takes it
Adults
Adult dose
Adults: Take 480 milligrams of r-thioctic acid tromethamine salt once daily with plenty of water, approximately 30 minutes before breakfast.

Ingredients

Manufacturer
Kunil Biopharm Co., Ltd.

Efficacy & effects

Relief of diabetic polyneuropathy

  • Diabetic polyneuropathy
View approved original text

This medication helps to alleviate nerve pain and discomfort caused by diabetic polyneuropathy. It is used to improve nerve function and enhance the quality of life for patients.

How to take

Adult dose

Adults: Take 480 milligrams of r-thioctic acid tromethamine salt once daily with plenty of water, approximately 30 minutes before breakfast.

Precautions

This medicine should not be used by anyone allergic to R-Lipoic Acid Trometamol, thioctic acid, or any other ingredients in this medication. While taking this medicine, side effects such as sensory abnormalities, pain, headache, constipation, dry mouth, and cough may occur, and in rare cases, serious side effects like kidney stones or facial swelling may develop. Additionally, some patients taking this medication have reported symptoms such as dry mouth, muscle pain, nausea, decreased appetite, and insomnia. Individuals who frequently consume alcohol may experience reduced efficacy of this medication, so it is advisable to avoid drinking as much as possible, including during the period after stopping the medication. This medicine may be less effective if taken with metallic-containing foods like iron, magnesium preparations, or milk, so if this medication is taken in the morning, it is recommended to take iron or magnesium in the afternoon or evening. Moreover, when taken in conjunction with insulin or oral antidiabetic medications, this drug may cause blood sugar to drop too low, so blood sugar levels should be checked frequently during the initial period of use, and medication dosages should be adjusted as necessary. Women who are pregnant or breastfeeding should consult a physician before taking this medication and should only use it after carefully evaluating its benefits and risks. Use in individuals under the age of 18 is not recommended due to insufficient evidence of safety and efficacy. In cases of overdose, severe toxic symptoms may occur, so immediate medical attention should be sought for appropriate treatment. This medication should be stored in a tightly closed container to prevent exposure to air or moisture and is best kept at room temperature between 1 to 30 degrees Celsius, out of reach of children, and should not be transferred to other containers.

Side effects

  • Paresthesia
  • pain
  • sensory loss
  • headache
  • constipation
  • abdominal discomfort
  • rhinitis
  • dry mouth
  • cough
  • cystitis
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  • diarrhea
  • burning sensation
  • nephrolithiasis
  • lumbar canal stenosis
  • facial swelling
  • dry mouth
  • myalgia
  • nausea
  • decreased appetite
  • arthralgia
  • palpitations
  • insomnia
  • upper extremity fractures
  • hypoglycemia
  • neurogenic bladder
  • diabetic retinopathy
  • colitis
  • benign gastric neoplasm
  • gastrointestinal bleeding
  • worsening of disease
  • soft tissue inflammation
  • common cold
  • body aches
  • plantar fasciitis
  • herniated disc
  • thyroiditis
  • increased LDH
  • increased triglycerides
  • weight loss
  • abnormal blood sugar
  • shingles
  • dysuria
  • deterioration of renal function
  • vulvovaginitis
  • conjunctivitis
  • floaters
  • unspecified retinal vascular disorder
  • heart palpitations
  • acute abdominal symptoms
  • colon polyps
  • benign oral neoplasm
  • benign gastrointestinal neoplasm
  • gastroesophageal reflux disease
  • gastritis
  • gastroenteritis
  • dental caries
  • periodontal disease
  • anal bleeding
  • chest pain
  • peripheral edema
  • edema
  • limb pain
  • carpal tunnel syndrome
  • flank pain
  • generalized edema
  • general weakness
  • low back pain
  • sleep disorders
  • simple partial seizures
  • facial paralysis
  • bitter taste
  • genital pruritus
  • nail changes
  • vesicles
  • dermatitis
  • unspecified peripheral vascular disease
  • gum bleeding
  • sputum diseases
  • bronchitis
  • throat infection
  • sinusitis
  • congestion
  • upper respiratory infection
  • allergic atopic rhinitis
  • respiratory distress
  • nausea
  • vomiting
  • gastrointestinal pain
  • skin rash
  • hives
  • itching
  • dizziness
  • sweating
  • taste disorder
  • epigastric pain
  • dyspepsia
  • pruritus
  • abdominal pain
  • heartburn
  • generalized convulsions
  • lactic acidosis
  • hypoglycemia
  • shock
  • rhabdomyolysis
  • hemolysis
  • disseminated intravascular coagulation
  • bone marrow suppression
  • multi-organ failure

Not everyone experiences these, and they can vary from person to person.

Storage

This medication should be stored in a tightly closed container to prevent air or moisture from entering. It is advisable to maintain the storage temperature between 1 to 30 degrees Celsius.

Appearance and packaging

Appearance

Light green, oblong, film-coated tablet

Package unit

30 tablets/bottle, 100 tablets/bottle

Same-ingredient medicines

Even with the same ingredient, strength, dosage form and how it is taken can differ.

Even with the same ingredient, the dose and directions can differ by strength and dosage form. Talk to a doctor or pharmacist before switching from a medication you are already taking.

Questions about this medicine

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For anything that needs medical judgment, consult a doctor or pharmacist.

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This drug information is based on data provided by the Korea Ministry of Food and Drug Safety.
Consult a doctor or pharmacist for accurate dosage, administration, and usage instructions.