Orobika Tablets 5/40 mg

Adult dose

This medication is taken once daily, with or without food, along with water. It is recommended to take it at the same time each day, if possible (e.g., in the morning). The recommended dosages are as follows: - 5/20 mg: Administer to patients whose blood pressure is not adequately controlled with amlodipine 5 mg or olmesartan medoxomil 20 mg monotherapy. - 10/20 mg: Administer to patients whose blood pressure is not adequately controlled with olmesartan medoxomil 20 mg monotherapy.

Child dose

Safety and efficacy for pediatric patients under 18 years have not been established.

This medication can cause serious harm to the fetus and newborn if taken during the second and third trimesters of pregnancy, so it must be discontinued immediately upon confirmation of pregnancy. Individuals who are allergic to any components of this medication or similar drugs, pregnant or breastfeeding women, patients with severe liver or heart diseases, patients with biliary obstruction, patients undergoing dialysis, and patients with certain kidney diseases or diabetes should not take this medication. Patients who are deficient in fluid or salt may experience hypotension, so caution is needed, and patients with sudden vascular dilation or weakened cardiac function should also take it carefully. This medication may cause side effects such as dizziness, headache, hypotension, cough, digestive disturbances, skin rash, muscle pain, and swelling, so any unusual symptoms should be discussed with a doctor. Especially during pregnancy, this medication can have serious effects on the fetus, so those planning to become pregnant or who are pregnant should consult with a doctor. During breastfeeding, this medication may pass into breast milk and affect the baby, so breastfeeding should be discontinued or medication should be stopped. It is not recommended for children under 18, as the safety and efficacy of this medication have not been established. Elderly patients may experience decreased kidney and liver function, so they should start with a low dose and take it with caution. Overdosing on this medication can lead to severe hypotension and cardiac dysfunction, so strict adherence to the prescribed dose is essential, and immediate medical attention is required in case of overdose. Taking this medication with grapefruit juice may excessively enhance the blood pressure-lowering effect, so co-administration should be avoided. Taking it with other antihypertensive medications or potassium-sparing diuretics may increase serum potassium levels, so regular blood tests are necessary. Store this medication out of reach of children, and avoid exposure to moisture, heat, and direct sunlight.

Serious side effects

Urticaria, severe swelling (angioedema), difficulty breathing, jaundice, sudden and very severe headache, seizures, confusion, vision disturbances, paralysis, significantly reduced urine output, serious systemic swelling with increased blood pressure, fainting, vascular edema, acute renal failure, toxic epidermal necrolysis, leukopenia, thrombocytopenia, worsened cerebral infarction

Mild side effects

• Dizziness
• headache
• orthostatic hypotension
• drowsiness
• abnormal sensation
• decreased sensation
• palpitations
• rapid heartbeat
• hypotension
• orthostatic hypotension

This medication should be stored in a tightly sealed container to avoid exposure to air and moisture. It is important to maintain a storage temperature between 1 degree and 30 degrees Celsius. Proper storage can help maintain the medication's efficacy for a long time.

Appearance

Pale yellow round film-coated tablets

Package unit

30 tablets/box [(10 tablets/PTP X 3)]