Olmesartan Medoxomil/Amlodipine Besylate/Hydrochlorothiazide Tablet 10/40/12.5 Milligrams

Adult dose

This medication should be taken once daily with water, regardless of meals. Taking it at the same time every day (e.g., in the morning) is recommended. The recommended dosages are as follows: - 5/20/12.5mg: for patients whose blood pressure is not adequately controlled with the combination therapy of amlodipine/olmesartan medoxomil 5/20mg. - 5/40/12.5mg: for patients whose blood pressure is not adequately controlled with the combination therapy of amlodipine/olmesartan medoxomil 5/40mg.

Child dose

The safety and efficacy for pediatric patients under 18 years of age have not been established, so administration of this medication is not recommended.

This medication can cause serious harm to the fetus and newborn in the second and third trimesters of pregnancy, so it must be discontinued immediately if pregnancy is confirmed. Patients with allergies to this medication or related drugs, or who have certain heart, kidney, or liver diseases should not take this medication. This medication is not suitable for patients with very low blood pressure or acute heart failure, severe kidney, or liver impairments. Patients with reduced blood volume or impaired kidney function, as well as those with certain heart valve diseases, should be cautious as this medication may cause hypotension or worsen kidney function. As this medication lowers blood pressure, it may cause dizziness or drowsiness, so caution should be taken when driving or operating dangerous machinery. During the use of this medication, regular checks of electrolyte levels and kidney function are necessary to ensure there are no abnormalities. Especially, patients with diabetes or impaired kidney function should not take this medication with certain others and should closely monitor blood pressure and kidney function while on this medication. This medication may cause sensitive skin reactions or photosensitivity in some patients, therefore protection from sun exposure is necessary, and any abnormal symptoms should be discussed with a physician. Elderly patients may be more sensitive to this medication, so starting with a low dose and using it cautiously is recommended. In cases of overdose, cardiovascular abnormalities such as hypotension and palpitations may occur, necessitating an immediate visit to a medical institution for appropriate treatment. The safety and efficacy of this medication has not been established in children, so its use is not recommended. Breastfeeding women should discontinue breastfeeding or stop taking this medication as its components may be transferred into breast milk. This medication should be stored in a location that avoids humidity, heat, and direct sunlight, out of reach of children.

Serious side effects

Hives, severe swelling (angioedema, Quincke's edema), chest tightness, difficulty breathing, cold sweat, pallor, severe rash with high fever, blistering, sloughing skin, pain in oral/ocular mucosa, difficulty breathing or dyspnea, asthma attack, respiratory abnormalities with cough and fever, yellowing of skin or eyes (jaundice), extreme lethargy, sudden and severe headache, lightning headache, seizures, confusion, vision changes

Mild side effects

• Peripheral edema
• headache
• dizziness
• upper respiratory tract infection
• nasopharyngitis
• urinary tract infection
• sialadenitis
• leukopenia
• thrombocytopenia
• bone marrow suppression

This medication may be sensitive to air or moisture, so it should be stored in a tightly sealed container. A storage temperature between 1 degree and 30 degrees Celsius is advisable. Storing it this way helps to maintain the medication's efficacy over time.

Appearance

Round film-coated tablet of grayish red color

Package unit

30 tablets/Alu-Alu [(10 tablets/Alu-Alu × 3)]